Search Bar & Filters
Found 2 Actively Recruiting clinical trials
Actively Recruiting
Researchers are evaluating Basic Body Awareness Therapy BBAT compared to stretching exercises for people with fibromyalgia. The study aims to see if BBAT can better reduce pain, improve biomarkers like serotonin, dopamine, and cortisol, and enhance psychological well-being and quality of life. This clinical trial involves randomized and controlled groups and includes patients diagnosed with fibromyalgia for at least six months. Participants will be divided into two groups one receiving BBAT and the other doing stretching exercises. BBAT sessions last 90 minutes and occur twice weekly for 12 weeks, focusing on movements of daily life, massage, and self-reflection. The stretching group will perform analytic stretching of the trunk and limbs for about 45 minutes twice a week for 12 weeks. Follow-up assessments will be done up to one year after treatment. During the study, participants will be assessed with various tools including the Fibromyalgia Impact Questionnaire, Visual Analog Scale, State Trait Anxiety Inventory, and Beck Depression Inventory. Biomarkers such as serotonin and cortisol will be measured at multiple points including post-treatment and during follow-up visits at 12 weeks, 24 weeks, and one year. The study includes detailed monitoring of psychological state, pain levels, and biological markers over the full duration.
Actively Recruiting
Researchers are evaluating whether ultrasound-guided alcohol sclerotherapy can reduce pelvic pain and improve quality of life in women aged 18 to 45 diagnosed with ovarian endometriomas. This study compares sclerotherapy to expectant management to determine which approach better helps manage symptoms and quality of life impacts associated with this common form of endometriosis. Participants are randomly assigned to either receive ultrasound-guided alcohol sclerotherapy involving puncture and alcohol treatment of the cysts or to be managed expectantly with standard pain management if needed. The sclerotherapy procedure involves a 15-minute application of absolute ethanol followed by a wash. Both groups will be followed for six months, with assessments at baseline and 6 months post-treatment. During the study, participants will complete quality of life and pain assessments using standardized tools, provide blood and urine samples for biomarker analysis, and undergo ovarian reserve evaluations. Researchers will monitor adverse events, cyst recurrence, fertility outcomes, and healthcare costs. Pregnancy outcomes will be followed for an average of two years. The main outcome is quality of life measured at baseline and 6 months.