Genc

This research investigates the effects of Yellow and Red Light Emitting Diode photobiomodulation on dry age-related macular degeneration (AMD). The study aims to determine if this treatment can reduce drusen volume and improve visual acuity and contrast sensitivity in people affected by dry AMD. Participants will be randomly assigned to either receive the photobiomodulation treatment or a sham (placebo) treatment. The treatment involves two cycles, each with two phases per session. In the first phase, participants receive 300 seconds of continuous Yellow light with their eyes closed, followed by 60 seconds of pulsed Yellow light with eyes open. The second phase includes 300 seconds of continuous Red light with eyes closed and 60 seconds of pulsed Red light with eyes open. Cycle 1 includes 8 sessions over 4 weeks (two sessions per week), and Cycle 2 includes 6 sessions over 3 weeks (two sessions per week). The sham group receives a low light emission mask. Participants will be monitored for changes in best corrected visual acuity, drusen volume, and contrast sensitivity at 1 month, 2 months, and 4 months after each treatment cycle. Researchers will assess both objective signs and subjective symptoms of dry AMD to evaluate the effects of the photobiomodulation. The study includes safety and compliance evaluations throughout the treatment and follow-up periods.