Iskenderun

Breast cancer is one of the most common and deadly cancers among women worldwide, with a high frequency especially in women aged 45 to 54. Chemotherapy, a common treatment for breast cancer, can cause significant side effects such as pain, nausea, fatigue, anxiety, and depression, which may reduce patients quality of life. This research aims to compare the effects of laughter yoga and mindfulness-based stress reduction MBSR on anxiety, depression, quality of life, and spiritual well-being in women receiving chemotherapy for breast cancer. Women participating in this study will be randomly assigned to one of three groups a laughter yoga group, a mindfulness therapy group, or a control group receiving standard hospital care. Both the laughter yoga and mindfulness therapy groups will attend sessions twice a week for 8 weeks, each lasting 40 to 60 minutes. The 9th and 16th sessions will be held face to face during chemotherapy treatment, while other sessions will be conducted online by smartphone at mutually convenient times. After 12 weeks, all groups will complete follow-up assessments. Participants will undergo evaluations using the Hospital Anxiety and Depression Scale to measure anxiety and depression symptoms, the European Organization for Research and Treatment of Cancer Quality of Life Scale to assess quality of life, and a Spiritual Well-being Scale to evaluate spiritual health. Assessments will be completed at the 4th and 8th weeks during face-to-face meetings and again at 12 weeks. The study includes monitoring adherence and excludes participants who cannot attend at least 80% of sessions. The total study duration for participants is approximately 12 weeks.