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Found 4 Actively Recruiting clinical trials
Actively Recruiting
Parkinsons disease can cause speech and voice problems like reduced loudness and clarity, which affect patients and families quality of life. This research evaluates the Lee Silverman Voice Therapy-LOUD LSVT-LOUD, a specialized speech therapy, in Turkish-speaking adults with Parkinsons disease aged 40 to 80. The study aims to assess objective vocal improvements and participants subjective experiences to support adapting this therapy for Turkish speakers. The study provides intensive LSVT-LOUD therapy involving four 60-minute individual sessions per week over four weeks. This therapy includes daily vocal exercises such as sustained vowel phonation, pitch range drills, and functional speech tasks progressing from words to conversation. Participants also receive carryover exercises for daily practice to help maintain improvements. A control group receives standard medical care without intensive speech therapy during the study. Participants attend therapy sessions and complete follow-up assessments immediately after therapy, at one month, and at three months. Researchers measure vocal loudness, acoustic voice stability, and fundamental frequency, along with patient-reported outcomes like voice handicap and Parkinsons disease quality of life. The study monitors therapy experiences and speech changes to evaluate the therapys impact over time.
Actively Recruiting
Healthy Volunteer
This research aims to evaluate the effect of a psychoeducation intervention based on the positive psychotherapy balance model on caregivers of individuals with colorectal cancer. The study focuses on improving balanced life, psychological well-being, and self-efficacy among these caregivers. It is conducted as a randomized controlled experimental trial with pretest, posttest, and follow-up assessments. The study also considers participants socio-demographic and caregiving characteristics as control variables. Caregivers will be randomly assigned to either an intervention group or a control group. The intervention group will receive face-to-face psychoeducation sessions based on the positive psychotherapy balance model over 5 weeks, with one 90-120 minute session each week. The control group will have a single 60-minute information session after 3 weeks. After completing the sessions, both groups will undergo post-testing, and follow-up data will be collected 3 months later. After the study ends, the control group will also receive the psychoeducation program. Participants will complete several assessments including the Balanced Life Scale, Psychological Well-Being Scale, and General Self-Efficacy Scale at baseline, after the sessions, and at follow-up. Researchers will collect data on caregivers balanced life levels, psychological well-being, and self-efficacy. The study will monitor attendance and completion of all sessions and tests. The total participation lasts over approximately 5 weeks plus a 3-month follow-up period, with ethical approvals and informed consent obtained prior to participation.
Actively Recruiting
Researchers are studying women aged 18 to 55 years who have non-anemic iron deficiency to understand the risk of developing anemia and to evaluate the effects of oral iron therapy. The study aims to identify early signs that predict anemia progression and to assess how dietary changes and iron treatment impact symptoms and blood test results. This research focuses on individual factors related to iron deficiency and its management. Participants first undergo a two-month nutritional intervention where they receive counseling to increase iron intake and absorption through diet. After this phase, blood tests categorize participants into groups based on their iron status. Those with persistent iron deficiency then receive a daily oral dose of 80 mg elemental iron ferrous sulfate for one month. Adherence and symptoms are monitored regularly by phone and clinic visits throughout both phases. During the study, participants complete symptom questionnaires and have blood tests to measure hemoglobin, ferritin, iron levels, and inflammatory markers at the start, after the nutritional phase, and following the iron therapy. Researchers track changes in symptoms and laboratory values to evaluate the effects of the interventions. The total study period includes two months of diet counseling and one month of oral iron treatment, with ongoing monitoring to assess safety and response.
Actively Recruiting
Healthy Volunteer
This research aims to evaluate the immediate effects of a single session of core stabilization exercises on balance and upper body functional performance in competitive archers. Archery demands precise postural stability, balance, and upper limb control, with core muscles playing a key role in trunk stability and effective force transfer. While long-term benefits of core exercises are known, this study focuses on their short-term impact as a warm-up strategy. Participants are randomly assigned to one of two groups one group performs a single session of core stabilization exercises targeting deep and superficial trunk muscles using static and dynamic exercises on various surfaces, while the control group performs no additional exercise. The exercises emphasize trunk control, posture alignment, and muscle activation to assess their immediate influence on performance. Assessments include pre- and immediate post-intervention measures of lower extremity balance, upper extremity functional performance, hand reaction time, grip strength, and shoulder muscle strength. The trial monitors these outcomes to understand how core exercises may improve archery-related skills and help optimize warm-up protocols. Participation involves a single session with evaluations conducted before and right after the intervention.