Karesi

This research focuses on patients diagnosed with Rheumatoid Arthritis (RA), a chronic and progressive inflammatory disease. The study aims to investigate how the use of medications with anticholinergic properties affects anticholinergic load and the risk of bone fractures in RA patients. Since long-term corticosteroid use in RA is known to increase fracture risk, the study uses the Fracture Risk Assessment Tool (FRAX) to evaluate fracture risk alongside measures of anticholinergic burden. The study will include 100 adult patients diagnosed with rheumatoid arthritis and followed in outpatient clinics at a physical medicine and rehabilitation department. Bone mineral density will be measured using Dual Energy X-ray Absorptiometry (DEXA). Anticholinergic load will be assessed using established scales such as the Anticholinergic Drug Scale, Anticholinergic Cognitive Burden Scale, and Anticholinergic Risk Scale. Patients' medication histories, blood test results, and bone density measurements from the past year will be recorded and analyzed. Participants will have their demographic data, systemic health conditions, and medication use reviewed. Blood tests including kidney and liver function, calcium and vitamin D levels, and hormone levels will be considered. Researchers will monitor anticholinergic burden and fracture risk using validated tools one week after the study start. The study will provide insight into how medications with anticholinergic effects may influence bone health in people with rheumatoid arthritis.

Researchers are studying how cognitive load affects walking and balance in people with Motoric Cognitive Risk Syndrome (MCRS). The study looks at how performing thinking tasks while walking impacts movement and balance. This research aims to better understand early signs of cognitive decline and the risk of falling in this group. Participants will complete standardized walking tests, including the Timed Up and Go (TUG) and tandem walking tests. These tests will be done under two conditions: single-task (just walking) and dual-task (walking while doing a mental task like serial subtraction). No treatments, exercise programs, or therapies will be given during the study. During the study, participants will be assessed once at baseline with the Timed Up and Go test. Researchers will measure how performing a mental task while walking affects gait and balance. The study focuses on cognitive-motor interference and dual-task cost to identify early markers of cognitive decline and fall risk in older adults with MCRS.

Researchers are comparing the effects of two different exercise programs on walking and thinking abilities in older adults aged 65 and above who have Motor Cognitive Risk (MCR) syndrome. MCR is a condition considered a transitional stage between normal aging and early signs of dementia or mild cognitive impairment. This study is the first to directly compare neuromuscular exercise training with a structured exergaming program in this population. The study involves two exercise programs lasting 8 weeks, with sessions twice a week for 45 minutes in groups of two. One program is neuromuscular exercise training, which includes warm-up, strengthening, balance, and motor control exercises with visual feedback, gradually increasing in difficulty. The other program uses Xbox One Kinect exergames incorporating warm-up, lower and upper body exercises, and cognitive tasks, with game difficulty increasing over time. Participants will be assessed from enrollment to the end of treatment at 8 weeks using tests measuring mobility and cognitive function, such as the Timed Up and Go Test, Stair Climbing Test, and a cognitive version of these tests. Researchers will monitor walking speed, balance, and cognitive changes throughout the study to understand how each exercise program affects these functions in elderly individuals with MCR syndrome.

Researchers are evaluating how effective exercises combined with ergonomics training are for construction workers. The study focuses on male workers aged 25 to 55 who have experienced pain in areas like the back, knee, neck, wrist, or shoulder for at least three months. This randomized controlled trial takes place in the Edremit district of Balikesir and is conducted by a physiotherapist. It aims to address work-related illnesses affecting musculoskeletal health among construction workers. Participants will be divided into two groups: one will receive only ergonomics training, while the other will get both exercise and ergonomics training. The ergonomics training covers topics such as the purpose of ergonomics, musculoskeletal diseases in employees, and work-related musculoskeletal risk factors. The exercise program includes stretching, strengthening, waist and core exercises, and relaxation techniques. Treatments will occur three times a week, each lasting 45 to 60 minutes, over a period of 12 weeks. Throughout the study, adherence to the exercise program will be tracked using an exercise chart. Researchers will assess outcomes after 14 weeks using tools like the Pittsburgh Sleep Quality Index, Maslach Burnout Scale, Nordic Musculoskeletal Questionnaire, and Fatigue Severity Scale. These assessments will help measure changes in sleep quality, burnout, musculoskeletal symptoms, and fatigue. Safety and progress will be monitored by the physiotherapist during treatment sessions.

This research aims to compare the effects of two different essential oils, rosa damascena and frankincense, on labor pain, anxiety, and comfort during childbirth. The study focuses on pregnant women in labor, exploring whether these oils can help improve comfort and reduce anxiety and pain. While rosa damascena has shown some effectiveness in previous studies for labor pain, there is limited information about its impact on comfort and anxiety, and frankincense oil's effects are also being investigated. Participants will inhale essential oils during labor as part of the study. The researchers will compare groups using rosa damascena oil, frankincense oil, or potentially other groups to assess how each oil affects the women's experience of labor pain, anxiety, and comfort. The study is designed as a randomized controlled trial to evaluate which essential oil provides more benefit during labor. During the study, pregnant women will be monitored for their pain levels, anxiety, and comfort within three hours of labor using specific measurements. The researchers will observe how the inhaled oils influence these outcomes and track any differences between the groups. Safety and any allergic reactions, especially to the oils, will also be considered. The total participation duration corresponds to the labor period during which these effects are measured.

Researchers are evaluating the Figure-of-8 Walk Test (8FWT) to determine its validity and reliability in people aged 65 and older who have Motoric Cognitive Risk Syndrome (MCRS). This study focuses on assessing how well the test measures dynamic balance, walking ability, and the interaction between cognitive and motor functions. It aims to confirm the test's usefulness in clinical settings by examining its consistency over time and its relationship with other mobility measures. Participants will take part in a series of non-invasive assessments including the 8FWT and the Timed Up and Go (TUG) test. These tests are designed to evaluate gait performance and balance without providing any treatment. The study involves only these evaluations with no therapeutic interventions applied. During the study, participants' walking speed, number of steps, and time to complete the Figure-of-8 Walk Test will be measured. Researchers will also assess functional mobility and cognitive-motor interaction. Participants must be able to walk independently and follow test instructions. The study focuses on older adults and monitors their performance to better understand the test's accuracy and reliability.

Researchers are examining how foot arch structure relates to walking patterns and cognitive function in adults aged 65 and older. The study looks at foot arch integrity using the Navicular Drop Test and measures walking performance with the 10-Meter Walk Test. It also explores cognitive-motor interactions by assessing lower limb reaction time using a light-based system in an observational cross-sectional design. Participants will undergo observational assessments without any treatment. Foot arch structure will be evaluated first, followed by tests measuring walking speed, step cadence, step length, and time spent with both feet on the ground. Reaction time tests will assess cognitive-motor function. These assessments are done in a single session without intervention. During the study visit, participants will complete walking tests and reaction time evaluations. Researchers will measure gait speed, cadence, step length, and double support time. The study focuses on understanding how these physical and cognitive factors interrelate in older adults. Participants must be able to walk independently and understand the procedures to complete the assessments.

Osteoporosis is a progressive bone disease marked by low bone mass and weakened bone structure, leading to a higher risk of fractures. This condition, along with related fractures, poses a major public health challenge globally, especially in aging populations. The study aims to assess health literacy and osteoporosis awareness among older adults at risk for osteoporosis, including both men and women, and to explore factors affecting these outcomes. Participants will complete questionnaires measuring health literacy and osteoporosis awareness. Health literacy is evaluated with the Turkish Health Literacy Scale-32 (THLS-32), which covers treatment, services, disease prevention, and health promotion. Osteoporosis awareness is measured using the Osteoporosis Awareness Scale, which assesses knowledge about bone physiology, preventive behaviors, risk factors, exercise, and osteoporosis characteristics. No medical tests or interventions will be performed. During the study, participants' age, sex, and education will be recorded. Researchers will analyze questionnaire results to understand literacy and awareness levels. The primary outcomes include the THLS-32 score and Osteoporosis Awareness Scale score after 6 months. Safety monitoring is not required as no interventions or tests will be conducted. Participation involves completing questionnaires and providing basic demographic information.

Researchers are evaluating how kinesiotaping affects pain and function in people with isolated meniscus injuries of the knee. This study is a randomized controlled trial including adults aged 18 to 50 who have knee pain lasting more than two weeks and a confirmed diagnosis of isolated meniscus injury. The goal is to compare the effects of different treatments on pain and knee function using measures like the Visual Analog Scale (VAS) and the WOMAC score over three months. Participants will be randomly divided into three groups. One group will receive standard treatment consisting of strengthening exercises for the quadriceps and hamstring muscles, stretching around the knee, proprioceptive exercises, and activity modifications to be done at home five days a week for three weeks. The second group will receive the same standard treatment plus kinesiotaping applied three times every five days using a specific technique and tension. The third group will receive standard treatment plus sham taping, where tape is applied without tension and without medication. Throughout the study, patients' age, gender, and body mass index will be recorded. Pain and knee function will be assessed before treatment, on day 20, and three months after treatment using VAS and WOMAC scores. The study monitors participants' progress and measures changes in pain and functionality to assess the effects of kinesiotaping compared to standard treatment alone or with sham taping.

Researchers are evaluating the validity and reliability of neuroscience-based visual laser feedback map tests in people with Motoric Cognitive Risk Syndrome (MCRS). This assessment combines visuospatial processing, reaction time, and upper body motor control into one task. The study aims to confirm how well the test measures these abilities by comparing it with reaction time and proprioception tests, and to check if the test produces consistent results over time. Participants will perform the visual laser feedback map test, which integrates several cognitive and motor skills. The study focuses on those aged 65 and older with MCRS, involving subjective cognitive complaints and slow walking speed. No additional treatment or intervention is mentioned, as the study mainly assesses the test's performance and reliability. During the study, participants will complete the laser feedback test and other measurements related to reaction time and proprioception. Researchers will analyze the results to determine the test's accuracy and consistency. The main outcome is the baseline performance on the visual laser feedback map test. Participants must be able to understand and complete the procedures, and the study monitors cognitive and motor function over the course of testing.