Kent

Researchers are reviewing anonymous medical records from multiple centers to understand the outcomes of different treatments for chronic pain. This study includes several groups to assess how various approaches work in distinct patient subgroups. The focus is on patients who have had or may have spinal cord stimulation systems or other treatments like radiofrequency RF or intradiscal therapies IDS. The study looks at patients who have previously received spinal cord stimulation or other therapies and those who have switched to different treatments afterward. Treatments under review include Boston Scientific devices and non-Boston Scientific systems such as spinal cord stimulation, RF, and IDS. The data is retrospective, meaning it examines past patient experiences without introducing new treatments. Participants involvement consists of the analysis of their de-identified medical charts, with no active treatment or visits required. Researchers will measure responder rates approximately two years from the start of data collection to evaluate treatment outcomes. The study spans from April 2012 to December 2030, focusing on long-term clinical results in chronic pain management.

Trichotillomania TTM is a condition marked by repeated hair pulling that causes hair loss and significant distress. Researchers are evaluating two digital health approaches to support adults with TTM using a randomized trial design. The study aims to compare the effects of these digital interventions on TTM symptoms over an 8-week period. Participants will be randomly assigned to one of two 8-week interventions. One group receives a Keen2 bracelet that detects hair pulling motions and vibrates to prompt awareness, along with a smartphone app offering behavior therapy components like psychoeducation and competing response training. The other group uses a non-vibrating reminder bracelet paired with an app delivering general health tips and prompts for logging daily context. During the study, participants will use their assigned devices and apps for 8 weeks. Researchers will assess trichotillomania symptom severity at the study endpoint week 8 through clinician ratings and self-reports. Participants must have reliable internet and a compatible mobile phone. Safety is monitored by requiring a support person and excluding those with severe psychiatric conditions. The total participation lasts approximately 8 weeks from intervention start to final assessments.

This trial investigates the use of a digital awareness tool for adults with trichotillomania, a hair-pulling disorder. Designed as a single-arm feasibility study, it evaluates how a wrist-worn Keen2 awareness bracelet paired with a mobile app can help detect and manage hair-pulling behavior. The study aims to assess usability, adherence, and changes in hair-pulling severity over an eight-week period. Participants will wear the Keen2 bracelet for eight weeks. During the first four weeks, the device detects hair-pulling episodes, and participants log details like emotions, location, and activity after each event. In weeks five through eight, the system delivers personalized vibration alerts based on prior behavior to encourage strategies such as reducing environmental triggers, practicing competing hand movements, and using coping techniques. Throughout the study, participants will engage with the device and app daily, providing contextual data and responding to alerts. Researchers will measure changes in hair-pulling severity using the Massachusetts General Hospital Hairpulling Scale and NIMH Trichotillomania Symptom Severity scores at baseline, week 4, and week 8, with follow-up at week 12. The study also examines participant feedback on device helpfulness and knowledge of intervention strategies to evaluate overall feasibility and behavioral impact.