Dripping Springs

Researchers are evaluating the effectiveness of an Activities-Based Locomotor Training (AB-LT) program compared to usual physical therapy for young children with Cerebral Palsy (CP) who are unable to walk. This study focuses on improving quality of life and motor function by targeting body structures, activities, and participation based on the World Health Organization's International Classification of Functioning framework. The goal is to enhance understanding of neuroplasticity and motor learning to develop more personalized and effective rehabilitation therapies that reduce disability and long-term healthcare needs. The AB-LT treatment involves placing the child in a partial body-weight supported system over a treadmill where trained clinicians assist the child in standing and walking for one hour. This is followed by one hour of play-based activities designed to encourage independence in regular environments. The final hour of each three-hour session is spent again in the partial body-weight support system focusing on standing and walking. The comparison group will continue their usual physical therapy sessions. Participants attend the AB-LT intervention five days a week for three weeks. During the study, children will be assessed using the Gross Motor Function Measure (GMFM-66) at four times: before treatment, at the end of week 3, week 4, and week 7. Families commit to a total of seven weeks in the study, continuing usual care when not in the AB-LT intervention. Researchers will monitor motor function improvements and safety throughout the study period to understand the benefits of this therapy for non-ambulatory children with CP.