Dripping Springs

Researchers are evaluating the effectiveness of an Activities-Based Locomotor Training AB-LT program compared to usual care to improve the quality of life and motor function in young children with Cerebral Palsy CP who are not able to walk independently. This study focuses on children aged 2 to 6 years and aims to understand how targeted physical activities can enhance brain function and movement, potentially leading to better, personalized therapies and reduced long-term healthcare needs. Participants in the study will be randomly assigned to either the AB-LT program or continue with their usual care. The AB-LT intervention involves a 3-week intensive training where children attend sessions 5 days a week, each lasting 3 hours. Each session includes walking and standing in a harness on a treadmill for 1 hour, followed by 1 hour of play-based physical therapy to encourage independence, and finishing with another hour of treadmill walking and standing. The usual care group continues their regular therapy schedule, which may include physical, occupational, or speech therapy with no restrictions on therapy type or amount. During the study, children will be assessed at four times at the start, after 3 weeks, after 4 weeks, and after 7 weeks. Assessments include measuring gross motor function using the GMFM-66, brain activity with functional near infrared spectroscopy fNIRS, and daily life engagement with the Child Engagement in Daily Life CEDL tool. The study lasts a total of 7 weeks, and children continue their usual care when not participating in the AB-LT sessions. Licensed physical therapists trained in AB-LT will supervise all intervention sessions to monitor progress and safety.