Montpelier

This research study focuses on individuals, including both adults and children, diagnosed with Chronic Granulomatous Disease (CGD). The study aims to understand how common certain antibodies against adenovirus and inflammatory proteins called cytokines are in people with CGD by measuring their levels in the blood. Blood samples will be collected from participants to measure the amount of adenovirus-specific antibodies and inflammatory cytokines circulating in their bodies. This is an observational study, meaning participants will not receive any treatments as part of the research; instead, their blood markers will be analyzed to learn more about their immune response. Participants will provide blood samples during the study, and the researchers will analyze these samples for total adenoviral-specific antibody levels and adenoviral-specific neutralizing antibody levels. The study also involves measuring inflammatory cytokines. The results will help characterize the prevalence of these markers in people with CGD. Participants or their guardians must provide informed consent and be able to follow study procedures.