Montpelier

This research study focuses on participants of all ages diagnosed with Chronic Granulomatous Disease CGD, a condition characterized by defective NADPH oxidase activity or specific genetic mutations. The study aims to understand how common certain adenovirus antibodies and inflammatory cytokines are in this group by measuring their levels in the blood. This observational study is sponsored by Ensoma and seeks to provide insight into immune markers in CGD patients. Participants will provide blood samples to allow researchers to measure total adenoviral-specific antibody titers, adenoviral-specific neutralizing antibody titers, and circulating inflammatory cytokine levels. These measurements will be taken once during the study to characterize the prevalence of these immune markers in both adult and pediatric CGD patients. During the study, participants will have blood collected for analysis of the specified antibodies and cytokines. Researchers will evaluate the levels of these markers to better understand immune responses in CGD. The study requires only a single visit for sample collection and assessment. Safety and compliance will be monitored through the ability to complete the sample collection procedure, and the total participation time is limited to this one-day visit.