Actively Recruiting
Locomotor and Bladder Function in Individuals With Acute Spinal Cord Injury
Led by Claudia Angeli · Updated on 2026-05-04
16
Participants Needed
1
Research Sites
368 weeks
Total Duration
On this page
Sponsors
C
Claudia Angeli
Lead Sponsor
N
National Institute of Neurological Disorders and Stroke (NINDS)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The loss of movement and walking ability significantly affects quality of life after spinal cord injury. In addition, bladder dysfunction consistently ranks as one of the top disorders affecting quality of life after spinal cord injury. The overall objective of this study is to demonstrate that epidural stimulation may be a method for improving stepping, standing and bladder function in individuals with spinal cord injury. With the use of epidural stimulation, the investigators propose to investigate how well the participant can stand and walk and how well the participant's bladder can store or hold urine as well as void or empty urine. The results of this study may aid in the development of treatments to help individuals with spinal cord injuries that are unable to stand or walk and have impaired bladder function.
CONDITIONS
Official Title
Locomotor and Bladder Function in Individuals With Acute Spinal Cord Injury
Who Can Participate
Eligibility Criteria
You may qualify if you...
- At least 18 years of age
- Non-progressive spinal cord injury
- Stable medical condition
- Inability to stand and step independently
- Unable to voluntarily move all individual joints of the legs
- No current anti-spasticity medication regimen
- No Botox injections in the prior six months
- Bladder dysfunction as a result of spinal cord injury
- Spinal cord injury between T1 and T10
- Injury occurred no greater than 1 year prior
You will not qualify if you...
- Ventilator dependent
- Untreated painful musculoskeletal dysfunction, fracture, or pressure sore
- Untreated psychiatric disorder or ongoing drug abuse
- Cardiovascular, respiratory, bladder, or renal disease unrelated to spinal cord injury
- Pregnant at the time of enrollment or planning to become pregnant during the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Kessler Foundation - Center for Spinal Stimulation
West Orange, New Jersey, United States, 07052
Actively Recruiting
Research Team
L
Leighann Martinez
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here