Actively Recruiting

Phase Not Applicable
Age: 18Years - 85Years
All Genders
NCT05081713

Locomotor Recovery and Compensation Post-stroke (LRC)

Led by Indiana University · Updated on 2026-03-05

150

Participants Needed

1

Research Sites

338 weeks

Total Duration

On this page

Sponsors

I

Indiana University

Lead Sponsor

R

Rehabilitation Hospital of Indiana

Collaborating Sponsor

AI-Summary

What this Trial Is About

The proposed research will characterize of the time course of neurological and locomotor recovery as well as development of compensatory strategies throughout sub-acute and chronic phases post stroke. In addition, we will also investigate the extent to which measures of recovery and compensation are malleable and can be altered with specific interventions in both the early and late stages post-stroke. Delineation of the time course of development and magnitude of patterns of recovery and compensation should result in alternative predictive "rules' regarding how patients early post-stroke could recovery functional and neurological function.

CONDITIONS

Official Title

Locomotor Recovery and Compensation Post-stroke (LRC)

Who Can Participate

Age: 18Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Individuals early post-stroke (less than 15-30 days)
  • First ever stroke
  • Unilateral hemiparesis (weakness on one side)
  • Currently receiving inpatient rehabilitation
  • Ability to follow one-step commands
  • Provision of informed consent
  • Medical clearance from rehabilitation physician to participate
Not Eligible

You will not qualify if you...

  • Uncontrolled cardiovascular, metabolic, or respiratory disease limiting exercise participation (e.g., congestive heart failure, resting blood pressure > 200/110 mmHg, uncontrolled diabetes, end-stage renal disease)
  • Absolute criteria for stopping exercise testing during initial or repeated ECG tests according to ACSM guidelines
  • Other orthopedic or neurological disorders limiting walking before the stroke

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Rehabilitation Hospital of Indiana

Indianapolis, Indiana, United States, 46254

Actively Recruiting

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Research Team

T

Thomas G Hornby

CONTACT

C

Chris Henderson

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

TREATMENT

Number of Arms

2

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