Actively Recruiting

Phase 3
Age: 18Years +
All Genders
NCT07225712

A Long-term Administration Trial of SEP-363856 in Patients With Schizophrenia

Led by Otsuka Pharmaceutical Co., Ltd. · Updated on 2026-01-14

100

Participants Needed

1

Research Sites

114 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To evaluate the safety of SEP-363856 (75 mg/day or 100 mg/day) administered for 52 weeks in adult participants with schizophrenia

CONDITIONS

Official Title

A Long-term Administration Trial of SEP-363856 in Patients With Schizophrenia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Japanese male or female participants 18 years of age or older at the time of informed consent
  • Diagnosed with schizophrenia according to the DSM-5�ae
  • Clinically stable for at least 8 weeks before screening
  • PANSS total score of 80 or less and CGI-S score of 4 or less at screening and baseline
  • No changes in antipsychotic medication for at least 6 weeks before screening (except minor dose adjustments for tolerability)
Not Eligible

You will not qualify if you...

  • History of psychiatric hospitalization within 8 weeks prior to screening
  • Treatment-resistant to antipsychotic therapy within 1 year before screening despite adequate doses of two or more antipsychotics for at least 4 weeks
  • History of treatment with clozapine
  • Unwillingness to comply with medication and therapy requirements during the trial or use of prohibited medications at screening or baseline

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Jimbo Kokorono Clinic

Fukuoka, Japan

Actively Recruiting

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Research Team

D

Drug Information Center

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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A Long-term Administration Trial of SEP-363856 in Patients With Schizophrenia | DecenTrialz