Actively Recruiting
Long-term Anticoagulation in a Patient With Severe Hemophilia A
Led by University Hospital, Strasbourg, France · Updated on 2026-01-02
1
Participants Needed
1
Research Sites
18 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To date, and to our knowledge, no case of severe hemophilia A patients receiving long-term anticoagulation has been published. Severe hemophilia A is a hereditary bleeding disorder characterized by a factor VIII (FVIII) deficiency of \<1%. Anticoagulation remains a real challenge in these patients, given the precarious hemostatic balance between the bleeding risk associated with anticoagulation and the antithrombotic protection associated with factor VIII deficiency. The advent of new replacement therapies, characterized by FVIII molecules with a prolonged or very prolonged half-life, provides a high level of FVIII coverage (and therefore protection against the risk of bleeding) in patients receiving prophylaxis, thus facilitating the initiation of anticoagulation therapy.
CONDITIONS
Official Title
Long-term Anticoagulation in a Patient With Severe Hemophilia A
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patient (≥ 18 years) with severe hemophilia A
- No written objection in the subject's medical record to reuse of their data for scientific research purposes
You will not qualify if you...
- Subject having expressed objection to the reuse of their data for scientific research
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Laboratoire d'Hématologie - Unité d'Hémostase - CHU de Strasbourg - France
Strasbourg, France, 67091
Actively Recruiting
Research Team
L
Laurent SATTLER, PharmD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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