Long-term Benefits of Continuous Positive Pressure Therapy or Mandibular Advancement Device on the Sleep of Patients With Obstructive Sleep Apnea

What this Trial Is About

Researchers are following 400 patients diagnosed with obstructive sleep apnea (OSA) across about ten sleep centers in France to study the long-term effects of two common treatments: continuous positive airway pressure (CPAP) and mandibular advancement device (MAD). The study focuses on how one year of treatment influences sleep quality and architecture, as well as patients' reported quality of life. The research also aims to identify factors that predict improvements in sleep quality during treatment. Participants will use either a fixed-pressure CPAP device, which includes remote monitoring capabilities, or a custom-made MAD created from dental impressions by a specialist. Sleep will be monitored at home using a connected sleep test device over one year. This observational study collects routine clinical data to compare the impact of these treatments on sleep patterns. Throughout the study, participants will undergo sleep tests with the Sunrise device and complete assessments of their sleep quality and life quality. The main outcome measured is the change in deep slow-wave sleep after one year of treatment. Researchers will also collect clinical information to understand how these treatments affect sleep over time and monitor participants to ensure ongoing safety and study adherence.

Long-term Benefits of CPAP or MAD Treatment on the Sleep of OSAS Patients