Actively Recruiting
Long Term Effect of Allergen Immunotherapy in Children with Allergy
Led by Odense University Hospital · Updated on 2025-07-10
100
Participants Needed
2
Research Sites
21 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to study the long-term effects of allergen immunotherapy in children with allergies. It focuses on children aged 5 to 18 years undergoing treatment with subcutaneous or sublingual immunotherapy for allergens such as grass pollen, birch, house dust mites, or venom. The study is observational and takes place in a real-life setting to understand lasting outcomes after immunotherapy. Children treated at Hans Christian Andersen Children's Hospital, Odense University Hospital, will be followed. Before starting immunotherapy, consent will be obtained to register data and send questionnaires 5 and 10 years after treatment ends. Baseline data includes symptoms, medication use, blood tests, and skin prick results. During treatment, yearly monitoring of symptoms, medication, lung function, and side effects will occur. Participants will receive questionnaires 5 and 10 years after treatment to assess allergy and asthma symptoms and medication use. The main outcome measured is the effect of immunotherapy 5 years after treatment, with a secondary outcome at 10 years. This long-term follow-up helps researchers understand how immunotherapy impacts children’s allergies over time.
CONDITIONS
Brief Title
Long Term Effect of AIT in Children
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children aged 5 to 18 years treated with allergen immunotherapy at Hans Christian Andersen Children's Hospital, Odense University Hospital
You will not qualify if you...
- Received less than 12 months of allergen immunotherapy treatment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - At least 12 months
Participants receive allergen immunotherapy as part of their usual care while the study observes the long-term effects of the treatment.
Annual visits during treatment
Duration - 10 years after treatment ends
Participants complete questionnaires 5 and 10 years after the end of treatment to assess allergy symptoms, medication use, and asthma symptoms.
2 follow-up questionnaire contacts (at 5 and 10 years post-treatment)
Trial Site Locations
Total: 2 locations
1
Hans Christian Andersen Children's Hospital
Odense, Odense C, Denmark, 5000
Actively Recruiting
2
Hans Christian Andersen Children's Hospital
Odense, Denmark, 5000
Actively Recruiting
Research Team
J
Josefine Gradman, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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