Long Term Study of Allergen Immunotherapy Effects in Children Aged 5 to 18 Years

What this Trial Is About

This research aims to study the long-term effects of allergen immunotherapy in children with allergies. It focuses on children aged 5 to 18 years undergoing treatment with subcutaneous or sublingual immunotherapy for allergens such as grass pollen, birch, house dust mites, or venom. The study is observational and takes place in a real-life setting to understand lasting outcomes after immunotherapy. Children treated at Hans Christian Andersen Childrens Hospital, Odense University Hospital, will be followed. Before starting immunotherapy, consent will be obtained to register data and send questionnaires 5 and 10 years after treatment ends. Baseline data includes symptoms, medication use, blood tests, and skin prick results. During treatment, yearly monitoring of symptoms, medication, lung function, and side effects will occur. Participants will receive questionnaires 5 and 10 years after treatment to assess allergy and asthma symptoms and medication use. The main outcome measured is the effect of immunotherapy 5 years after treatment, with a secondary outcome at 10 years. This long-term follow-up helps researchers understand how immunotherapy impacts childrens allergies over time.

Long Term Effect of AIT in Children