Actively Recruiting
A Long Term Extension Study to Evaluate the Safety and Efficacy of Afimkibart (RO7790121) in Participants With Atopic Dermatitis
Led by Hoffmann-La Roche · Updated on 2026-05-11
120
Participants Needed
14
Research Sites
372 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will assess long-term safety and efficacy of Afimkibart (also known as RO7790121) in participants with Atopic Dermatitis (AD) who participated in previous afimkibart clinical trials.
CONDITIONS
Official Title
A Long Term Extension Study to Evaluate the Safety and Efficacy of Afimkibart (RO7790121) in Participants With Atopic Dermatitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ability and willingness to comply with all study procedures including efficacy assessments and sample collections
- Participation in parent study CS45570 with evaluation at Week 36 follow-up
- Achieved 50% or greater improvement (EASI50 response) from baseline in parent study
You will not qualify if you...
- Presence of other skin conditions that interfere with Atopic Dermatitis assessment
- Withdrawal of consent or early discontinuation from the parent study
- Permanent discontinuation of study drug in the parent study
- History of severe allergic or anaphylactic reaction to any biologic agent or known hypersensitivity to any component of Afimkibart
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 14 locations
1
Hamilton Research, LLC
Alpharetta, Georgia, United States, 30022
Actively Recruiting
2
Revival Research Institute, LLC
Troy, Michigan, United States, 48084
Actively Recruiting
3
Best Skin Research LLC
Camp Hill, Pennsylvania, United States, 17011
Actively Recruiting
4
Irmandade Da Santa Casa de Misericordia de Porto Alegre
Porto Alegre, Rio Grande do Sul, Brazil, 90020-090
Actively Recruiting
5
Instituto Brasil de Pesquisa Clínica-IBPCLIN S/A
Rio de Janeiro, Brazil, 20241-180
Actively Recruiting
6
DermEffects
London, Ontario, Canada, N6H 5L5
Actively Recruiting
7
DermEdge
Mississauga, Ontario, Canada, L4Y4C5
Actively Recruiting
8
Dermatologikum Hamburg Gemeinschaftspraxis GbR
Hamburg, Germany, 20354
Actively Recruiting
9
Centrum Medyczne Pratia Katowice I
Katowice, Silesian Voivodeship, Poland, 40-081
Actively Recruiting
10
Centrum Medyczne Pratia Gdynia
Gdynia, Poland, 81-338
Actively Recruiting
11
Specjalistyczny Gabinet Dermatologiczny dr n. med. Pawel Brzewski
Krakow, Poland, 30-002
Actively Recruiting
12
Centrum Nowoczesnych Terapii "Dobry Lekarz"
Krakow, Poland, 31-011
Actively Recruiting
13
Uniwersytecki Szpital Kliniczny im.Fryderyka Chopina w Rzeszowie
Rzeszów, Poland, 35-055
Actively Recruiting
14
Klinika Ambroziak Dermatologia
Warsaw, Poland, 02-953
Actively Recruiting
Research Team
R
Reference Study ID Number: CS45943 https://forpatients.roche.com/
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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