Actively Recruiting

All Genders
NCT05713214

Long-term Follow-up After Adoptive Transfer of Genetically Modified Cell Products

Led by St. Jude Children's Research Hospital · Updated on 2025-07-01

1000

Participants Needed

1

Research Sites

1555 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Human gene therapy products are designed to achieve therapeutic effect through genetic modifications of human cells using retroviral or lentiviral vectors, resulting in permanent or long-acting changes in the human body. With this genetic modification comes risk of undesirable adverse events. Due to this risk, the Food and Drug Administration (FDA) and the Center for Biologics Evaluation and research (CBER) require long-term follow-up (15 years) of participants that receive investigational gene therapy products that meet defined criteria. This protocol will provide a mechanism by which to appropriately monitor participants that have received a genetically modified cellular product on a St. Jude initiated study.

CONDITIONS

Official Title

Long-term Follow-up After Adoptive Transfer of Genetically Modified Cell Products

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Receipt of a genetically modified cell product on a St. Jude investigator-initiated study within the prior 15 years.
Not Eligible

You will not qualify if you...

  • Inability or unwillingness of research participant and/or legal guardian/ representative to give written informed consent.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

St. Jude Children's Research Hospital

Memphis, Tennessee, United States, 38105

Actively Recruiting

Loading map...

Research Team

A

Aimee Talleur, MD

CONTACT

S

Swati Naik, MBBS

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here