Actively Recruiting

Phase 3
Age: 0Years - 100Years
All Genders
NCT05335876

Long-term Follow-up of Patients With Spinal Muscular Atrophy Treated With OAV101 in Clinical Trials

Led by Novartis Pharmaceuticals · Updated on 2026-01-20

175

Participants Needed

32

Research Sites

427 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a global, prospective, multi-center study that is designed to assess the long-term safety and efficacy of OAV101 in patients who participated in an OAV101 clinical trial. The assessments of safety and efficacy in Study COAV101A12308 will continue for 5 years after enrollment in this study.

CONDITIONS

Official Title

Long-term Follow-up of Patients With Spinal Muscular Atrophy Treated With OAV101 in Clinical Trials

Who Can Participate

Age: 0Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participated in an OAV101 clinical trial.
  • Provided written informed consent before any assessments.
  • Patient, parent, or legal guardian willing and able to follow study procedures.
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 32 locations

1

Child Hosp Of The Kings Daughters

Norfolk, Virginia, United States, 23507

Actively Recruiting

2

Novartis Investigative Site

Sydney, New South Wales, Australia, 2031

Actively Recruiting

3

Novartis Investigative Site

Leuven, Belgium, 3000

Actively Recruiting

4

Novartis Investigative Site

Curitiba, Paraná, Brazil, 81520-060

Actively Recruiting

5

Novartis Investigative Site

São Paulo, São Paulo, Brazil, 05403 000

Actively Recruiting

6

Novartis Investigative Site

Montreal, Quebec, Canada, H4A 3J1

Actively Recruiting

7

Novartis Investigative Site

Chongqing, Chongqing Municipality, China, 400010

Actively Recruiting

8

Novartis Investigative Site

Guangzhou, Guangdong, China, 510623

Actively Recruiting

9

Novartis Investigative Site

Chengdu, Sichuan, China, 610041

Actively Recruiting

10

Novartis Investigative Site

Beijing, China, 100034

Actively Recruiting

11

Novartis Investigative Site

Beijing, China, 100069

Actively Recruiting

12

Novartis Investigative Site

Beijing, China, 100730

Actively Recruiting

13

Novartis Investigative Site

Copenhagen, Denmark, 2100 O

Actively Recruiting

14

Novartis Investigative Site

Bron, France, 69677

Actively Recruiting

15

Novartis Investigative Site

Garches, France, 92380

Actively Recruiting

16

Novartis Investigative Site

Strasbourg, France, 67000

Actively Recruiting

17

Novartis Investigative Site

Toulouse, France, 31059

Actively Recruiting

18

Novartis Investigative Site

Roma, RM, Italy, 00168

Actively Recruiting

19

Novartis Investigative Site

Kurume, Fukuoka, Japan, 830-0011

Actively Recruiting

20

Novartis Investigative Site

Shinjuku Ku, Tokyo, Japan, 1628666

Actively Recruiting

21

Novartis Investigative Site

Kuala Lumpur, Malaysia, 50300

Actively Recruiting

22

Novartis Investigative Site

Kuala Lumpur, Malaysia, 59100

Actively Recruiting

23

Novartis Investigative Site

Utrecht, Netherlands, 3584 CX

Actively Recruiting

24

Novartis Investigative Site

Riyadh, Saudi Arabia, 11211

Actively Recruiting

25

Novartis Investigative Site

Singapore, Singapore, 119074

Actively Recruiting

26

Novartis Investigative Site

Barcelona, Spain, 08035

Actively Recruiting

27

Novartis Investigative Site

Kaohsiung City, Taiwan, 80756

Actively Recruiting

28

Novartis Investigative Site

Taipei, Taiwan, 10002

Actively Recruiting

29

Novartis Investigative Site

Bangkok, Thailand, 10700

Actively Recruiting

30

Novartis Investigative Site

London, United Kingdom, WC1N 3JH

Actively Recruiting

31

Novartis Investigative Site

Newcastle upon Tyne, United Kingdom, NE1 4LP

Actively Recruiting

32

Novartis Investigative Site

Hanoi, Vietnam, 100000

Actively Recruiting

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Research Team

N

Novartis Pharmaceuticals

CONTACT

N

Novartis Pharmaceuticals

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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