Actively Recruiting

Age: 20Years - 70Years
All Genders
NCT06277037

Long-Term Follow-up Study for Subjects With CHB Previously Treated With Imdusiran (AB729)

Led by Arbutus Biopharma Corporation · Updated on 2024-11-27

50

Participants Needed

18

Research Sites

276 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a long term follow-up study for chronic hepatitis B (CHB) subjects who have received imdusiran treatment in a prior clinical trial, stopped NA therapy during that trial, and remain off therapy. Subjects may enroll after completing the end of study visit (baseline visit within 12 weeks ± 1 week from the end of study \[EOS\] visit) from their imdusiran clinical trial (the "parent study"). No interventions will be performed in this study other than blood sample collections, review of current medications, and reporting of any adverse events related to study procedures or NA therapy if restarted. Study participation will be for approximately 2 years (to complete a total of at least 3 years of follow-up while off NA therapy, inclusive of parent study participation).

CONDITIONS

Official Title

Long-Term Follow-up Study for Subjects With CHB Previously Treated With Imdusiran (AB729)

Who Can Participate

Age: 20Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have participated in a prior imdusiran clinical trial
  • Have discontinued NA therapy in that trial and remain off NA therapy
  • Have completed less than 3 years of follow-up visits after NA discontinuation in the parent study
  • Have the ability to review and provide signed informed consent which includes compliance with all protocol-specified visit schedules and requirements
Not Eligible

You will not qualify if you...

  • Not applicable

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 18 locations

1

Research and Education Inc.

San Diego, California, United States, 92105

Actively Recruiting

2

University of Miami Miller School of Medicine

Miami, Florida, United States, 33136

Not Yet Recruiting

3

Infectious Disease Care

Hillsborough, New Jersey, United States, 08844

Actively Recruiting

4

The Alfred Hospital

Melbourne, Victoria, Australia, 3004

Actively Recruiting

5

Fiona Stanley Hospital

Murdoch, Australia, 6150

Not Yet Recruiting

6

Prince of Wales Hospital

Shatin, New Territories, Hong Kong

Actively Recruiting

7

Queen Mary Hospital

Hong Kong, Hong Kong

Actively Recruiting

8

Arensia Exploratory Medicine Moldova

Chisinau, Moldova

Actively Recruiting

9

Asan Medial Center

Seoul, South Korea, 05505

Not Yet Recruiting

10

Changhua Christian Hospital

Changhua, Taiwan, 600566

Actively Recruiting

11

Chia-Yi Christian Hospital

Chiayi City, Taiwan, 60002

Actively Recruiting

12

Kaohsiung Medical University Chung-Ho Memorial Hospital

Kaohsiung City, Taiwan, 80756

Actively Recruiting

13

E-Da Hospital

Kaohsiung City, Taiwan, 82445

Actively Recruiting

14

Taichung Veterans General Hospital

Taichung, Taiwan, 40705

Actively Recruiting

15

Chang Gung Medical Foundation Linkou

Taoyuan, Taiwan, 33305

Actively Recruiting

16

University Hospital of Wales, Cardiff

Cardiff, United Kingdom, CF144XW

Not Yet Recruiting

17

Royal London Hospital

London, United Kingdom, E11FR

Not Yet Recruiting

18

King's College Hospital

London, United Kingdom, SE59RS

Not Yet Recruiting

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Research Team

M

Michael Child

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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