Actively Recruiting
A Long-Term Open-Label Study of ML-007C-MA in Adults With Schizophrenia
Led by MapLight Therapeutics · Updated on 2026-04-22
500
Participants Needed
5
Research Sites
200 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
ML-007C-MA-212 is a 52-week open-label study designed to evaluate the long-term safety, tolerability, and effectiveness of ML-007C-MA in participants with schizophrenia who have recently completed an antecedent study (ML-007C-MA-211) or enroll directly (De Novo Cohort).
CONDITIONS
Official Title
A Long-Term Open-Label Study of ML-007C-MA in Adults With Schizophrenia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Able and willing to provide informed consent for all study procedures
- Have a primary diagnosis of schizophrenia based on DSM-5 criteria confirmed by clinical interview
- May benefit from long-term medication for schizophrenia as assessed by the investigator
- Suitable for outpatient care and live in a stable living situation as assessed by the investigator
- Have a reliable informant available to participate in assessments, such as site staff if in regular contact for over 1 year
You will not qualify if you...
- Have any DSM-5 disorder other than schizophrenia within the past 12 months that mainly causes current symptoms or problems
- Are stopping effective and well-tolerated antipsychotic treatment just to join this study
- Have used any prohibited therapy during screening unless stopped before baseline
- Have a clinically significant or unstable medical condition at screening or baseline
- Have abnormal physical exam, ECG, or safety lab results at screening or baseline
- Have a high risk of suicidal behavior
- Are allergic to ML-007C-MA or its ingredients
- Have moderate to severe substance use disorder (except tobacco or caffeine) within past 12 months
- Have a high risk of violent or destructive behavior based on history and investigator judgment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
Clinical Site
Lemon Grove, California, United States, 91945
Actively Recruiting
2
Clinical Site
Miami Lakes, Florida, United States, 33016
Actively Recruiting
3
Clinical Site
Chicago, Illinois, United States, 60640
Actively Recruiting
4
Clinical Site
Staten Island, New York, United States, 10314
Actively Recruiting
5
Clinical Site
DeSoto, Texas, United States, 75115
Actively Recruiting
Research Team
C
Clinical Trials Contact Center
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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