Actively Recruiting

Phase Not Applicable
Age: 22Years - 90Years
All Genders
NCT06500975

Long Term Outcomes After Vestibular Implantation

Led by Johns Hopkins University · Updated on 2026-03-09

32

Participants Needed

1

Research Sites

260 weeks

Total Duration

On this page

Sponsors

J

Johns Hopkins University

Lead Sponsor

N

National Institute on Aging (NIA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Although cochlear implants can restore hearing to individuals who have lost cochlear hair cell function, there is no widely available, adequately effective treatment for individuals suffering chronic imbalance, postural instability and unsteady vision due to bilateral vestibular hypofunction. Prior research focused on ototoxic cases has demonstrated that electrical stimulation of the vestibular nerve via a chronically implanted multichannel vestibular implant can partially restore vestibular reflexes that normally maintain steady posture and vision; improve performance on objective measures of postural stability and gait; and improve patient-reported disability and health-related quality of life. This single-arm open-label study extends that research to evaluate outcomes for up to 8 individuals with non-ototoxic bilateral vestibular hypofunction, yielding a total of fifteen adults (age 22-90 years at time of enrollment) divided as equally as possible between ototoxic and non-ototoxic cases.

CONDITIONS

Official Title

Long Term Outcomes After Vestibular Implantation

Who Can Participate

Age: 22Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults older than 22 years old
  • Previously enrolled in Johns Hopkins University Institutional Review Board protocols NA_00051349, IRB00335294, or IRB00346924
  • Previously implanted with a vestibular implant under FDA IDE G150198
Not Eligible

You will not qualify if you...

  • None specified

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Johns Hopkins School of Medicine

Baltimore, Maryland, United States, 21287

Actively Recruiting

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Research Team

K

Kelly Lane

CONTACT

C

Charles C Della Santina, MDPhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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