National Multicenter Study on Long-Term Effects of Conduction System Pacing including His Bundle or Left Bundle Branch Area Pacing

What this Trial Is About

Researchers are evaluating the long-term electrical, echocardiographic, and clinical outcomes of conduction system pacing CSP, which includes His Bundle Pacing or Left Bundle Branch Area Pacing. This observational study addresses the limited data currently available on the long-term results and benefits of CSP, especially focusing on the maintenance of physiological ventricular activation and conduction system capture over time. The study aims to provide reliable data on the preservation of CSP during a two-year follow-up period. Participants who have undergone a conduction system pacing attempt will be followed prospectively. Electrical data such as pacing thresholds, impedance, and R wave sensing will be collected during routine pacemaker check-ups to assess threshold stability. Echocardiographic evaluations will monitor changes in left ventricular ejection fraction LVEF and ventricular synchrony. Clinical data including the incidence of atrial fibrillation, heart failure hospitalizations, and NYHA stage will also be gathered to provide a comprehensive view of patient outcomes. Participants will undergo systematic follow-up visits over 24 months to record electrical parameters, heart function via echocardiography, and clinical status. The main outcome measured is freedom from major adverse events at 24 months. Secondary measures include LVEF, atrial fibrillation incidence, heart failure hospitalizations, conduction system pacing thresholds, paced QRS width, and ventricular dyssynchrony parameters. This long-term observation will help clarify the benefits and stability of CSP in a real-world setting.

Long-term Outcomes of Conduction System Pacing: a National Multicenter Observational Study - NORMAND'HIS / STIMU'HIS