Actively Recruiting
Long-term Prospective Study of Korean CADASIL Patients
Led by Jeju National University Hospital · Updated on 2026-05-14
500
Participants Needed
1
Research Sites
912 weeks
Total Duration
On this page
Sponsors
J
Jeju National University Hospital
Lead Sponsor
A
Asan Medical Center
Collaborating Sponsor
AI-Summary
What this Trial Is About
K-CADASIL is a 10-year prospective study of 500 Korean patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a genetic brain disease that causes stroke and dementia. The investigators will track symptoms, brain scans, memory tests, and gene information to understand disease progression in Koreans and identify better treatments. Participants will visit clinics regularly for check-ups and blood tests. This study aims to help improve care for CADASIL patients and families worldwide.
CONDITIONS
Official Title
Long-term Prospective Study of Korean CADASIL Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 6 19 years
- Suspected or confirmed CADASIL by genetic testing (NOTCH3 mutation)
- Able to provide written informed consent (participant or legally authorized representative)
You will not qualify if you...
- Contraindication to MRI such as claustrophobia, metal implants, or pacemaker
- Acute ischemic or hemorrhagic stroke within 180 days prior to enrollment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Jeju National University Hospital
Jeju City, Jeju-do, South Korea, 63241
Actively Recruiting
Research Team
J
Jay Chol Professor Choi, MD, PhD, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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