Actively Recruiting

Age: 18Years +
All Genders
NCT06407063

Long-term Reoperations After Lumbar Spinal Stenosis Surgery

Led by University Hospital of North Norway · Updated on 2024-12-17

794

Participants Needed

1

Research Sites

971 weeks

Total Duration

On this page

Sponsors

U

University Hospital of North Norway

Lead Sponsor

T

The Royal Norwegian Ministry of Health

Collaborating Sponsor

AI-Summary

What this Trial Is About

Severe and persisting pain and disability due to a degenerative narrowing of the spinal canal, lumbar spinal stenosis, can be operated with a simple surgical decompression. Sometimes, there is also a slippage of vertebra, degenerative spondylolisthesis. In such cases, instrumental stabilization (e.g. screws and rods) has been recommended. Even though additional fusion is more complex and riskier, and evidence in high-quality Scandinavian studies shows that it is unnecessary, decompression plus fusion is still the treatment of choice in the USA and most European countries. This reluctance to change clinical practice is mainly due to concerns about long-term results, especially higher reoperation rates among patients operated with decompression only. This register-based non-inferiority study aims to assess long-term reoperations among those treated with and without additional fusion surgery.

CONDITIONS

Official Title

Long-term Reoperations After Lumbar Spinal Stenosis Surgery

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Operated between September 2007 and December 2015 with both 'Spinal stenosis' and 'Degenerative spondylolisthesis' labeled in the registry
  • Underwent decompression surgery with or without additional fusion
Not Eligible

You will not qualify if you...

  • Operated using an anterior surgical approach
  • Had a previous operation at the index spinal level
  • Diagnosed with degenerative scoliosis
  • Operated on more than 2 spinal levels
  • Received non-instrumented fusion
  • In the micro-decompression group, operated with standard laminectomy removing posterior midline structures or without magnifying devices

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University hospital of North Norway

Tromsø, Norway, 9038

Actively Recruiting

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Research Team

E

Eirik Mikkelsen, MD

CONTACT

T

Tore Solberg, Prof

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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