Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT07114159

Long-term Safety and Efficacy of Sacral Nerve Stimulation in Patients With Ulcerative Colitis

Led by Xijing Hospital · Updated on 2025-08-11

15

Participants Needed

1

Research Sites

382 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Although the incidence of inflammatory bowel disease is stable in North American and European countries, the incidence of inflammatory bowel disease is increasing in newly industrialized countries, especially in China. The treatment drugs for ulcerative colitis include 5-aminosalicylic acid (5-ASA), glucocorticoids, immunosuppressants, and biological agents. The aim of this clinical trial is to evaluate the long-term safety and efficacy of sacral nerve stimulation in patients with ulcerative colitis

CONDITIONS

Official Title

Long-term Safety and Efficacy of Sacral Nerve Stimulation in Patients With Ulcerative Colitis

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 65 years
  • Diagnosis of ulcerative colitis for at least 3 months
  • Mayo score between 6 and 12 and Mayo endoscopic score of 2 to 3 points
  • Ulcerative colitis resistant to medical treatment
Not Eligible

You will not qualify if you...

  • Treatment-naive ulcerative colitis (no previous treatment)
  • Acute severe ulcerative colitis
  • Currently taking any biological treatments
  • Previous surgical treatment or severe colitis with imminent risk of surgery
  • Infective colitis
  • Other systemic diseases
  • Pregnancy and lactation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Xijing Hospital

Xi'an, Shaanxi, China, 710032

Actively Recruiting

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Research Team

J

Jian Wan

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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