Actively Recruiting
Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine
Led by Pfizer · Updated on 2026-05-14
600
Participants Needed
126
Research Sites
483 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to test the long-term safety of rimegepant in the acute treatment of migraine in children and adolescents (≥ 6 to \< 18 years of age).
CONDITIONS
Official Title
Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine
Who Can Participate
Eligibility Criteria
You may qualify if you...
- History of migraine (with or without aura) for at least 6 months before screening
- History of 1 to 8 moderate or severe migraine attacks per month during the 2 months before screening
- At least 1 migraine day requiring treatment during the Observation Phase
- Stable dose of preventive migraine medication for at least 12 weeks before screening is allowed
- Ability to distinguish migraine from other headaches
- Weight greater than 15 kg; for participants aged 12 to under 18 years in EU countries, weight must be over 25 kg
- Adequate venous access for blood sampling
- Male and female participants aged 6 to under 18 years who will not turn 18 before the Baseline visit
You will not qualify if you...
- History of cluster headache or hemiplegic migraine headache
- Presence of confounding and clinically significant pain syndrome
- Current uncontrolled or untreated psychiatric condition for at least 6 months before screening; lifetime history of psychosis or mania excluded
- History of suicidal behavior or risk of self-harm or harm to others
- History of major psychiatric disorder
- Current diagnosis or history of substance abuse
- Current use of or positive test for drugs of abuse at screening
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 126 locations
1
Perseverance Research Center, LLC
Scottsdale, Arizona, United States, 85253
Actively Recruiting
2
Physicians Research Group
Tempe, Arizona, United States, 85284
Active, Not Recruiting
3
Advanced Research Center, Inc.
Anaheim, California, United States, 92805
Actively Recruiting
4
ProScience Research Group
Culver City, California, United States, 90230
Actively Recruiting
5
Neuro-Pain Research Center
Fresno, California, United States, 93710
Actively Recruiting
6
Regents of the University of California (UC San Diego)
La Jolla, California, United States, 92093
Actively Recruiting
7
Adult & Child Neurology Medical Associates
Long Beach, California, United States, 90806
Actively Recruiting
8
Memorialcare Miller Children's & Women's Hospital Long Beach
Long Beach, California, United States, 90806
Actively Recruiting
9
Velocity Clinical Research - North Hollywood
North Hollywood, California, United States, 91606
Active, Not Recruiting
10
The Neurology Group
Pomona, California, United States, 91767
Actively Recruiting
11
UC Davis Medical Center, Investigational Drug Service (IDS) Pharmacy
Sacramento, California, United States, 95817
Active, Not Recruiting
12
University of California, Davis Clinical and Translational Science Center Clinical Research Center
Sacramento, California, United States, 95817
Active, Not Recruiting
13
University of California, Davis Midtown Clinic
Sacramento, California, United States, 95817
Active, Not Recruiting
14
Velocity Clinical Research- Banning
San Bernardino, California, United States, 92408
Actively Recruiting
15
Pacific Clinical Research Management Group LLC
Upland, California, United States, 91786
Active, Not Recruiting
16
Sunwise Clinical Research
Walnut Creek, California, United States, 94596
Actively Recruiting
17
Children's Hospital Colorado- Investigational Drug Services
Aurora, Colorado, United States, 80045
Actively Recruiting
18
Children's Hospital Colorado
Aurora, Colorado, United States, 80045
Actively Recruiting
19
Colorado Springs Neurological Associates, PC
Colorado Springs, Colorado, United States, 80907
Active, Not Recruiting
20
Colorado Springs Neurological Associates, PC
Colorado Springs, Colorado, United States, 80919
Active, Not Recruiting
21
Boeson Research GJT
Grand Junction, Colorado, United States, 81501
Terminated
22
Dinosaur Pediatrics
Grand Junction, Colorado, United States, 81501
Terminated
23
Boeson Research GJT
Grand Junction, Colorado, United States, 81505
Terminated
24
CT Clinical Research
Cromwell, Connecticut, United States, 06416
Actively Recruiting
25
Ki Health Partners, LLc, dba New England Institute for Clinical Research
Stamford, Connecticut, United States, 06905
Actively Recruiting
26
Children's National Medical Center
Washington D.C., District of Columbia, United States, 20010
Actively Recruiting
27
AppleMed Research Group, LLC
Miami, Florida, United States, 33126
Active, Not Recruiting
28
Medical Research Center of Miami II, Inc
Miami, Florida, United States, 33134
Active, Not Recruiting
29
South Florida Research Phase I-IV, Inc
Miami, Florida, United States, 33166
Actively Recruiting
30
Physicians Group Services, PA d/b/a Coastal Health Research
Orange Park, Florida, United States, 32073
Active, Not Recruiting
31
Clinical Associates of Orlando, LLC
Orlando, Florida, United States, 32819
Actively Recruiting
32
ForCare Clinical Research
Tampa, Florida, United States, 33613
Active, Not Recruiting
33
Premiere Research Institute at Palm Beach Neurology
West Palm Beach, Florida, United States, 33407
Active, Not Recruiting
34
Childrens Healthcare of Atlanta
Atlanta, Georgia, United States, 30329
Actively Recruiting
35
Rare Disease Research LLC
Atlanta, Georgia, United States, 30329
Active, Not Recruiting
36
Pivotal Clinical Research & Associates, LLC
Brunswick, Georgia, United States, 31520
Actively Recruiting
37
CenExel iResearch, LLC
Decatur, Georgia, United States, 30030
Actively Recruiting
38
Chicago Headache Center & Research Institute
Chicago, Illinois, United States, 60657
Actively Recruiting
39
AMR-Baber Research Inc
Naperville, Illinois, United States, 60563
Actively Recruiting
40
Options Research Group, LLC
Westfield, Indiana, United States, 46074
Actively Recruiting
41
Integrated Clinical Trial Services
West Des Moines, Iowa, United States, 50265
Actively Recruiting
42
Clinical Associates Midwest, LLC
Kansas City, Kansas, United States, 66214
Actively Recruiting
43
University of Kentucky Hospital
Lexington, Kentucky, United States, 40536
Active, Not Recruiting
44
Ochsner Clinic Foundation
New Orleans, Louisiana, United States, 70121
Terminated
45
MedVadis Research Corporation
Waltham, Massachusetts, United States, 02451
Active, Not Recruiting
46
Michigan Head Pain and Neurological Institute
Ann Arbor, Michigan, United States, 48104
Actively Recruiting
47
Corewell Health, for and on behalf of Spectrum Health Hospital and Corewell Health Medical Group
Grand Rapids, Michigan, United States, 49503
Actively Recruiting
48
Corewell Health, Helen DeVos Children's Hospital
Grand Rapids, Michigan, United States, 49503
Actively Recruiting
49
Wellnow Urgent Care and Research
Kalamazoo, Michigan, United States, 49048
Terminated
50
Beaumont Hospital, Royal Oak Campus
Royal Oak, Michigan, United States, 48073
Actively Recruiting
51
Sharlin Health Neuroscience Research Center
Ozark, Missouri, United States, 65721
Active, Not Recruiting
52
Clinvest Research, LLC
Springfield, Missouri, United States, 65807
Active, Not Recruiting
53
Boeson Research
Great Falls, Montana, United States, 59405
Actively Recruiting
54
Heart & Hands Midwifery
Kalispell, Montana, United States, 59901
Active, Not Recruiting
55
Blue Moose Pediatrics
Missoula, Montana, United States, 59804
Actively Recruiting
56
Boeson Research Laboratory
Missoula, Montana, United States, 59804
Actively Recruiting
57
Boeson Research
Missoula, Montana, United States, 59804
Actively Recruiting
58
Alivation Research, LLC
Lincoln, Nebraska, United States, 68526
Terminated
59
Children's Hospital & Medical Center
Omaha, Nebraska, United States, 68114
Actively Recruiting
60
HMH Jersey Shore University Medical Center
Neptune City, New Jersey, United States, 07753
Not Yet Recruiting
61
Hope Tower
Neptune City, New Jersey, United States, 07753
Not Yet Recruiting
62
Dent Neurosciences Research Center
Amherst, New York, United States, 14226
Actively Recruiting
63
True North Neurology
Commack, New York, United States, 11725
Actively Recruiting
64
New York Neurology Associates
New York, New York, United States, 10003
Actively Recruiting
65
Mount Sinai Hospital - Pharmacy Department
New York, New York, United States, 10029
Active, Not Recruiting
66
Columbia University Irving Medical Center
New York, New York, United States, 10032
Active, Not Recruiting
67
Irving Center for Clinical and Translational Research, Outpatient Clinical Research Unit
New York, New York, United States, 10032
Active, Not Recruiting
68
The Neurological Institute of New York
New York, New York, United States, 10032
Active, Not Recruiting
69
North Suffolk Neurology
Port Jefferson Station, New York, United States, 11776
Active, Not Recruiting
70
OnSite Clinical Solutions, LLC
Charlotte, North Carolina, United States, 28277
Actively Recruiting
71
Headache Wellness Center, PC
Greensboro, North Carolina, United States, 27405
Actively Recruiting
72
WellNow Urgent Care and Research
Cincinnati, Ohio, United States, 45215
Active, Not Recruiting
73
Cincinnati Children's Hospital
Cincinnati, Ohio, United States, 45229
Actively Recruiting
74
Velocity Clinical Research - Cincinnati
Cincinnati, Ohio, United States, 45242
Actively Recruiting
75
University Hospitals Cleveland Medical Center
Cleveland, Ohio, United States, 44106
Actively Recruiting
76
Wellnow Urgent Care and Research
Dayton, Ohio, United States, 45424
Active, Not Recruiting
77
IPS Research Company
Oklahoma City, Oklahoma, United States, 73106
Active, Not Recruiting
78
Velocity Clinical Research, Grants Pass
Grants Pass, Oregon, United States, 97527
Active, Not Recruiting
79
Providence Neuroscience Institute: Research Coordinators' Office
Portland, Oregon, United States, 97225
Actively Recruiting
80
Providence Pediatric Specialty Clinic
Portland, Oregon, United States, 97225
Actively Recruiting
81
Clario
Philadelphia, Pennsylvania, United States, 19103
Active, Not Recruiting
82
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States, 19104
Active, Not Recruiting
83
Velocity Clinical Research-Providence
East Greenwich, Rhode Island, United States, 02818
Actively Recruiting
84
Velocity Clinical Research- Greenville
Greenville, South Carolina, United States, 29615
Active, Not Recruiting
85
Premier Neurology
Greer, South Carolina, United States, 29650
Active, Not Recruiting
86
Novaceut Clinical Research
Clarksville, Tennessee, United States, 37043
Active, Not Recruiting
87
Le Bonheur Children's Hospital
Memphis, Tennessee, United States, 38103
Actively Recruiting
88
Le Bonheur Childrens Hospital - Childrens Foundation Research Institute
Memphis, Tennessee, United States, 38103
Actively Recruiting
89
Le Bonheur Childrens Hospital - Outpatient Building
Memphis, Tennessee, United States, 38103
Actively Recruiting
90
Access Clinical Trials, Inc.
Nashville, Tennessee, United States, 37203
Terminated
91
Dell Children's Medical Center
Austin, Texas, United States, 78723
Actively Recruiting
92
Child Neurology Consultants of Austin - South Austin
Austin, Texas, United States, 78749
Actively Recruiting
93
Child Neurology Consultants of Austin - Central Austin
Austin, Texas, United States, 78757
Actively Recruiting
94
Houston Clinical Trials, LLC
Bellaire, Texas, United States, 77401
Actively Recruiting
95
Infinite Research Group, LLC
Dallas, Texas, United States, 75201
Active, Not Recruiting
96
Cedar Health Research
Dallas, Texas, United States, 75251
Active, Not Recruiting
97
ANESC Research
El Paso, Texas, United States, 79912
Actively Recruiting
98
North Texas Institute of Neurology and Headache
Frisco, Texas, United States, 75034
Active, Not Recruiting
99
Trio Clinical Trials, LLC.
Houston, Texas, United States, 77008
Active, Not Recruiting
100
Pain and Headache Centers of Texas
Houston, Texas, United States, 77054
Actively Recruiting
101
SCLA Management
Houston, Texas, United States, 77077
Actively Recruiting
102
Houston Clinical Research,LLC.
Houston, Texas, United States, 77081
Terminated
103
NeuroCare Plus
Houston, Texas, United States, 77094
Actively Recruiting
104
AIM Trials, LLC
Plano, Texas, United States, 75093
Actively Recruiting
105
JBR Clinical Research
Salt Lake City, Utah, United States, 84107
Actively Recruiting
106
Wasatch Clinical Research , LLC(Administrative Location)
Salt Lake City, Utah, United States, 84107
Actively Recruiting
107
Pediatric Associates of Charlottesville, PLC (Private Pediatric Practice)
Charlottesville, Virginia, United States, 22902
Actively Recruiting
108
Pediatric Research of Charlottesville, LLC (Regulatory Only)
Charlottesville, Virginia, United States, 22902
Actively Recruiting
109
Pediatric Research of Charlottesville, LLC
Charlottesville, Virginia, United States, 22902
Actively Recruiting
110
Children's Hospital of The King's Daughters
Norfolk, Virginia, United States, 23507
Actively Recruiting
111
Children's Specialty Group, PLLC , Division of Childhood & Adolescent Neurology
Norfolk, Virginia, United States, 23510
Actively Recruiting
112
National Clinical Research, Inc.
Richmond, Virginia, United States, 23294
Terminated
113
Northwest Clinical Research Center
Bellevue, Washington, United States, 98007
Actively Recruiting
114
Seattle Children's Hospital Investigational Drug Services
Seattle, Washington, United States, 98105
Actively Recruiting
115
Seattle Children's Hospital
Seattle, Washington, United States, 98105
Actively Recruiting
116
University Hospital
Madison, Wisconsin, United States, 53792
Actively Recruiting
117
NZOZ Wielospecjalistyczna Poradnia Lekarska SYNAPSIS, Lech Szczechowski
Katowice, Poland, 40-123
Terminated
118
Centrum Medyczne Plejady
Krakow, Poland, 30-363
Actively Recruiting
119
Wojewodzki Specjalistyczny Szpital Dzieciecy im. Sw. Ludwika w Krakowie Oddzial Kliniczny Dzieci
Krakow, Poland, 31-503
Actively Recruiting
120
Clinical Research Center Sp. z o.o.
Poznan, Poland, 60-848
Actively Recruiting
121
Pracownia Badan Klinicznych SALUS
Wroclaw, Poland, 52-210
Actively Recruiting
122
Centrum Medyczne Oporow
Wroclaw, Poland, 52-416
Active, Not Recruiting
123
Centre Atencio Primaria (CAP) Balenya
Balenya, Barcelona, Spain, 08550
Active, Not Recruiting
124
Hospital Universitario Vall d'Hebron
Barcelona, Spain, 08035
Actively Recruiting
125
Hospital Universitario Virgen del Rocio
Seville, Spain, 41013
Actively Recruiting
126
Hospital Clinico Universitario de Valladolid
Valladolid, Spain, 47003
Actively Recruiting
Research Team
P
Pfizer Pfizer CT.gov Call Center
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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