Actively Recruiting
A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures
Led by Rapport Therapeutics Inc. · Updated on 2026-01-23
30
Participants Needed
7
Research Sites
111 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a clinical research study for an investigational drug called RAP-219 in patients with Refractory Focal Epilepsy. This study is being conducted to determine RAP-219 Long- term safety and open-label antiseizure activity in patients with Refractory Focal Epilepsy.
CONDITIONS
Official Title
A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Completion of the associated parent study (RAP-219-FOS-201) treatment period with acceptable tolerability, per Investigator
- Diagnosis of refractory focal epilepsy
- Stable RNS(c) system settings
- A demonstrated history of compliance with RNS(c) system data interrogation and upload
- Good overall health other than focal epilepsy, per Investigator
- BMI 6 18 kg/m^2 and 45 kg/m^2
- Willing and able to adhere to all aspects of the protocol
You will not qualify if you...
- Known hypersensitivity to RAP-219
- Any clinically unstable or serious medical, neurological (other than epilepsy), psychological, or behavioral problem; laboratory or ECG finding that would increase participant risk or should otherwise exclude the patient from participation, as assessed by Investigator
- Pregnancy, lactation, or individuals of reproductive potential who do not agree to simultaneously use two effective birth-control methods
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 7 locations
1
Consultants in Epilepsy and Neurology, PLLC
Boise, Idaho, United States, 83702
Actively Recruiting
2
Mayo Clinic
Rochester, Minnesota, United States, 55905
Actively Recruiting
3
NYU Langone Comprehensive Epilepsy Center
New York, New York, United States, 10016
Actively Recruiting
4
Cleveland Clinic Foundation
Cleveland, Ohio, United States, 44195
Actively Recruiting
5
University of Pennsylvania - Department of Neurology
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
6
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37232
Actively Recruiting
7
Baylor College of Medicine
Houston, Texas, United States, 770300
Actively Recruiting
Research Team
D
Daniela Moreno
CONTACT
B
Beth Bowers
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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