Actively Recruiting

Age: 75Years +
All Genders
Healthy Volunteers
NCT06374069

Longevity Families of the Netherlands

Led by Leiden University Medical Center · Updated on 2024-04-18

600

Participants Needed

1

Research Sites

168 weeks

Total Duration

On this page

Sponsors

L

Leiden University Medical Center

Lead Sponsor

J

Jacobijn Gussekloo, Prof. dr.

Collaborating Sponsor

AI-Summary

What this Trial Is About

The demographic life expectancy enhancement of the past 150 years imposes an urgent challenge in Western and economically growing societies to stimulate the healthy lifespan that is lagging behind. Families surviving into exceptionally high ages (longevity) in good physical and mental health illustrate that this is physiologically possible. Such families harbor cross generational socio-genetic mechanisms that mediate healthy aging and protection from (multi)morbidity. The purpose of our research is: to identify gene variants associated with healthy aging and protection from (multi)morbidity; to study the social-, environment- and behavioral factors of familial longevity, their role in (multi-)morbidity and its interaction with the genetic component.

CONDITIONS

Official Title

Longevity Families of the Netherlands

Who Can Participate

Age: 75Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Siblings of Dutch Caucasian descent age 75+ enriched for familial longevity
  • Individuals of Dutch Caucasian descent age 75+ who are not enriched for familial longevity
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

Leiden University Medical Center

Leiden, South Holland, Netherlands, 2333ZA

Actively Recruiting

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Research Team

(

(Eline) P. Slagboom, Prof. dr.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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