Genetic risk classification for adults with AML receiving less-intensive therapies: the 2024 ELN recommendations.
Hartmut Döhner, Courtney D DiNardo, Frederick R Appelbaum...
https://pubmed.ncbi.nlm.nih.gov/39133932/Actively Recruiting
Led by Tempus AI · Updated on 2026-07-21
550
Participants Needed
9
Research Sites
52 weeks
Total Duration
This research aims to gather detailed molecular and clinical data from patients with hematologic cancers like Acute Myeloid Leukemia AML and Follicular Lymphoma FL. It is an observational study designed to explore how biomarkers relate to real-world outcomes in these conditions by following patients over time. The study is conducted by Tempus AI and involves multiple patient groups with different disease stages and risks. Participants are grouped mainly into newly diagnosed AML patients and various subgroups of Follicular Lymphoma patients categorized by disease status and treatment plans. The study involves collecting blood samples and leftover tissue or bone marrow during their routine medical care and monitoring without any investigational treatments or interventions. These samples will be analyzed to understand disease progression and response. During the study, participants undergo serial blood draws and provide tissue or bone marrow samples as part of their normal care. Researchers will examine molecular markers and link these findings to clinical outcomes over five years. The study does not involve any treatments and focuses entirely on observation and data collection. Participation may last up to several years, with ongoing monitoring of health and disease status.
CONDITIONS
A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies
A
Aquarius Clinical Study Manager
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Tempus AI
Lead Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 5 years
Participants provide blood samples and leftover tissue or bone marrow during their routine care and disease monitoring visits. These samples are analyzed to study biomarkers over time.
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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Lead Sponsor