Actively Recruiting
Longitudinal Study for Central Nervous System Vasculitis
Led by University of Pennsylvania · Updated on 2026-01-23
40
Participants Needed
6
Research Sites
408 weeks
Total Duration
On this page
Sponsors
U
University of Pennsylvania
Lead Sponsor
T
The Cleveland Clinic
Collaborating Sponsor
AI-Summary
What this Trial Is About
Primary central nervous system vasculitis (CNSV) is a potentially fatal, single-organ vasculitis that often involves a spectrum of neurologic complications, including strokes, cognitive and speech impairment, visual loss, dementia, and encephalopathy. The purpose of this study is to establish a research cohort to investigate the disease process, treatments, and patient outcomes in CNSV.
CONDITIONS
Official Title
Longitudinal Study for Central Nervous System Vasculitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of primary central nervous system vasculitis confirmed by neurologic deficits
- Presence of classic angiographic or histopathologic features of angiitis in the central nervous system
- No evidence of systemic vasculitis or other conditions causing similar features
- Age 18 years or older
You will not qualify if you...
- Unwillingness to sign informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 6 locations
1
Mayo Clinic
Rochester, Minnesota, United States, 55905
Actively Recruiting
2
Cleveland Clinic
Cleveland, Ohio, United States, 44195
Actively Recruiting
3
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
4
Vanderbilt University
Nashville, Tennessee, United States, 37232
Actively Recruiting
5
St. Joseph's Healthcare
Hamilton, Canada
Actively Recruiting
6
University of Toronto/Sinai Health
Toronto, Canada
Actively Recruiting
Research Team
C
Carol McAlear
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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