Actively Recruiting

Age: 8Years - 18Years
All Genders
ID05816174

Child and Parent Emotion-related Risk and Resilience Factors Associated With the Transition From Acute to Chronic Pain After Surgery: A Prospective Longitudinal Study

Led by Helen Koechlin · Updated on 2026-04-29

281

Participants Needed

3

Research Sites

N/A

Total Duration

On this page

Sponsors

H

Helen Koechlin

Lead Sponsor

U

University of Zurich

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are conducting a study to understand chronic postsurgical pain in children and adolescents aged 8 to 18 years. This pain develops or worsens after surgery and affects about 20% of young patients after major operations, impacting their quality of life. The study focuses on how emotional factors like emotion variability, regulation, and differentiation may influence the risk of developing this long-term pain, which has not been studied before in this context. This observational study involves five assessments: one before surgery and four follow-ups after surgery. These assessments track changes in pain and emotional factors over time to identify those that increase or decrease the risk of chronic postsurgical pain. The study takes place in participating children's hospitals where planned orthopedic surgeries requiring inpatient care occur. Participants will be evaluated through repeated measurements over a year, including pain levels at 3 and 12 months, emotional changes, and physical activity at 3 months. The researchers will monitor pain trajectories and emotional patterns to better understand how these factors relate to chronic pain development. The total participation involves scheduled assessments before and after surgery to gather detailed data on these outcomes.

CONDITIONS

Brief Title

Longitudinal Study of Chronic Postsurgical Pain in Children and Adolescents

Who Can Participate

Age: 8Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Children and adolescents aged between 8 and 18 years
  • Planned orthopedic surgery requiring in-patient care in one of the participating children's hospitals
  • Able to read and understand German
Not Eligible

You will not qualify if you...

  • Serious comorbid health condition (e.g., cancer, severe neurological impairment, chronic illness requiring daily medication)
  • Prior major orthopedic surgery (e.g., prior spine surgery)
  • Parent/caregiver and child not able to read and understand German

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Up to 3 months

Participants undergo assessments related to pain and emotion after surgery.

1 to 2 visits depending on assessments

Long-term Monitoring

Duration - Up to 12 months

Participants are observed to monitor the progression of chronic postsurgical pain and related emotional trajectories over time.

Periodic visits over 12 months

Trial Site Locations

Total: 3 locations

1

University Children's Hospital Basel

Basel, Switzerland

Actively Recruiting

2

University Children's Hospital Zurich

Zurich, Switzerland, 8032

Actively Recruiting

3

University Hospital Balgrist

Zurich, Switzerland

Actively Recruiting

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Research Team

H

Helen Koechlin, PhD

J

Jana Hochreuter, MSc

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Published Research Related To This Trial

Longitudinal Resilience and Risk Factors in Pediatric Postoperative Pain (LORRIS): Protocol for a Prospective Longitudinal Swiss University Children's Hospitals-Based Study.

Jana Hochreuter, Thomas Dreher, Carol-Claudius Hasler...

https://pubmed.ncbi.nlm.nih.gov/38548365