Actively Recruiting

Age: 14Years +
All Genders
ID06752304

A Longitudinal Study of Severe and Enduring Eating Disorders Tracking Clinical, Psychological, and Biological Risk Factors in Adolescents and Adults

Led by Uppsala University Hospital · Updated on 2024-12-31

800

Participants Needed

1

Research Sites

1265 weeks

Total Duration

On this page

Sponsors

U

Uppsala University Hospital

Lead Sponsor

F

Forte

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this observational longitudinal study is to investigate characteristics and factors associated with the development of Severe and Enduring Eating Disorders (SEED). In this project, the researchers will follow two prospective cohorts of patients with eating disorders (ED), one adolescent (ages 14-17) and one adult (ages 18+), in terms of change in and impact of clinical, psychological, and biological risk factors. Data will be collected at baseline, after treatment, two years after baseline, and thereafter five, 10 and 20 years after baseline. Participants will be asked to undergo a physical examination, leave blood samples, be interviewed, and fill in questionnaires. If the participants are minors, their care takers will also fill in the questionnaires. The study aims to explore how clinical, psychological, and biological risk factors-including comorbidity, personality characteristics, difficulties with emotion regulation (ER), cognitive inflexibility, loneliness, severe ED symptoms, and inflammatory activation-contribute to a chronic course of the disorder.

CONDITIONS

Official Title

A Longitudinal Study of Severe and Enduring Eating Disorders

Who Can Participate

Age: 14Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

Inclusion criteria:

  • found to meet the criteria for an eating disorder
  • being in need of treatment
  • having provided written informed consent (for minors, this includes consent from all caregivers and the minors themselves).

Exclusion criteria:

  • Eating disorders symptoms in need of emergency care
  • High risk for suicide
  • An inability to respond to the questionnaires due to e.g., lack of knowledge in Swedish.
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

Uppsala University Hospital

Uppsala, Sweden, 75185

Actively Recruiting

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Research Team

M

Martina Isaksson, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Published Research Related To This Trial

Social Disconnectedness, Loneliness, and Mental Health Among Adolescents in Danish High Schools: A Nationwide Cross-Sectional Study.

Ziggi Ivan Santini, Veronica S C Pisinger, Line Nielsen...

https://pubmed.ncbi.nlm.nih.gov/33927599

Emotion generation and regulation in anorexia nervosa: a systematic review and meta-analysis of self-report data.

Anna Oldershaw, Tony Lavender, Hannah Sallis...

https://pubmed.ncbi.nlm.nih.gov/26043394

Research Review: What we have learned about the causes of eating disorders - a synthesis of sociocultural, psychological, and biological research.

Kristen M Culbert, Sarah E Racine, Kelly L Klump

https://pubmed.ncbi.nlm.nih.gov/26095891