Actively Recruiting
Losartan for Corneal Fibrosis
Led by Universidad Autonoma de Nuevo Leon · Updated on 2026-05-08
46
Participants Needed
1
Research Sites
54 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a prospective, randomized, double-blinded, controlled clinical trial designed to evaluate the efficacy and safety of topical losartan in improving visual acuity, contrast sensitivity and reducing corneal densitometry, corneal aberrations and corneal scarring severity in adult patients with corneal scars of different etiologies. Participants will be randomly assigned to receive either topical losartan 0.8 mg/mL or placebo eyedrops 6 times per day for six months.
CONDITIONS
Official Title
Losartan for Corneal Fibrosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older
- Presence of corneal scar with a duration of at least 1 month
- Corneal scars of any cause
- Corneal scars with or without new blood vessel growth
- Stable corneal scar without any open or fragile surface areas
- No active treatment for the corneal condition for at least 1 month
You will not qualify if you...
- Unable or unwilling to provide written informed consent
- Presence of corneal epithelial defect or fragile corneal surface
- Under 18 years of age
- Pregnant
- Known allergy or sensitivity to losartan
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Ophthalmology Department
Monterrey, Nueo Leon, Mexico, 64460
Actively Recruiting
Research Team
K
Karim Mohamed-Noriega, Dr. med.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here