Development and Validation of a Low-Cost Multimodal Mobile Colposcope for Cervical Cancer Prevention in Women

What this Trial Is About

Cervical cancer is a leading cause of cancer death among women in many low- and middle-income countries. Prevention efforts in these areas face challenges such as shortages of skilled personnel, lack of pathology services, and limited infrastructure. This research aims to develop and validate a low-cost Multimodal Mobile Colposcope MMC that combines mobile colposcopy and fiber-optic confocal microscopic imaging to improve cervical cancer screening and diagnosis globally. Participants in this study will undergo imaging during their colposcopy examination using the MMC device. This includes capturing images or videos of the cervix with both the mobile colposcope and the confocal imaging probe. Cervical biopsies will also be performed following standard clinical protocols as part of the evaluation process. Women referred for colposcopy due to abnormal cervical screening or follow-up for cervical dysplasia will take part in this study. Researchers will collect imaging data and perform biopsies to develop and validate the MMC device on the day of colposcopy. The primary measure is the performance of the MMC device during this examination. Participants will be monitored during their visit, and their informed consent will be obtained before participation.

Low-cost Imaging Technology for Global Prevention of Cervical Cancer