Actively Recruiting

Phase 3
Age: 18Years - 65Years
All Genders
NCT04928300

Low Dose Dexmedetomidine Versus Normal Saline in Multiple Fracture Ribs

Led by Assiut University · Updated on 2026-01-02

60

Participants Needed

1

Research Sites

319 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In our study, we assess the diaphragmatic function, pain quality and anti-inflammatory properties between low dose infusion of dexmedetomidine normal saline in patients with multiple fracture ribs on conservative treatment.

CONDITIONS

Official Title

Low Dose Dexmedetomidine Versus Normal Saline in Multiple Fracture Ribs

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 65 years with ASA physical status I-II
  • Traumatic multiple rib fractures involving three or more ribs confirmed by chest 3D-CT
  • Receiving conservative treatment such as chest strappings
  • Experiencing intractable pain with a visual analogue scale over 6 despite traditional therapies
  • Glasgow Coma Scale score of 13 or higher
Not Eligible

You will not qualify if you...

  • Multiple traumatic injuries to other body parts with an abbreviated injury scale over 3
  • Serious head trauma with Glasgow Coma Scale less than 13
  • Patients requiring mechanical ventilation
  • Presence of massive hemothorax
  • Injury to trachea or bronchus necessitating immediate surgery
  • Dementia diagnosis
  • Use of corticosteroids during ICU stay
  • Sepsis
  • Ongoing use of neuromuscular blocking agents or aminoglycoside antibiotics
  • Known hypersensitivity or contraindication to the study drugs

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Assiut university hospital

Asyut, Assuit, Egypt, Assuit universi

Actively Recruiting

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Research Team

O

Omar Soliman, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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