Actively Recruiting

Phase 2
Age: 18Years - 65Years
All Genders
NCT07451652

Low Dose Epcoritamab Plus GemOx in R/R DLBCL

Led by Hospital Universitario Dr. Jose E. Gonzalez · Updated on 2026-04-01

10

Participants Needed

1

Research Sites

76 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In this study, researchers are looking to determine whether Gemcitabine/Oxaliplatin plus a lower dose of Epcoritamab (12 mg) works to treat subjects with relapsed/refractory diffuse large B-cell lymphoma, who are candidates to autologous stem cell transplantation.

CONDITIONS

Official Title

Low Dose Epcoritamab Plus GemOx in R/R DLBCL

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have relapsed or refractory diffuse large B-cell lymphoma and have had at least one prior treatment
  • Eligible for autologous stem cell transplantation
  • ECOG performance status between 0 and 2
  • Women of childbearing potential agree to use contraception
  • Meet Lugano criteria for disease activity
  • Voluntarily agree to participate in the study
Not Eligible

You will not qualify if you...

  • Have an active bacterial, viral, or fungal infection
  • Have previously received autologous or allogeneic stem cell transplantation
  • Have other active cancers
  • Have end-stage organ failure

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hospital Universitario "Dr. José Eleuterio González"

Monterrey, Nuevo León, Mexico, 64640

Actively Recruiting

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Research Team

P

Perla R Colunga-Pedraza, MD

CONTACT

N

Natalia Huergo-Treviño, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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