Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
All Genders
NCT02502162

Low-Dose Naltrexone for the Treatment of Complex Regional Pain Syndrome

Led by Stanford University · Updated on 2025-05-29

120

Participants Needed

1

Research Sites

630 weeks

Total Duration

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AI-Summary

What this Trial Is About

The investigators are testing treatment with low-dose naltrexone (LDN) for symptom relief of complex regional pain syndrome (CRPS). Study participants will be randomly assigned to receive either LDN or placebo for a period of several weeks. During this period participants will be asked to attend either in-person or virtual study visits and complete questionnaires.

CONDITIONS

Official Title

Low-Dose Naltrexone for the Treatment of Complex Regional Pain Syndrome

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Upper and/or lower extremity complex regional pain syndrome (CRPS)
  • On stable treatment for at least 1 month
  • CRPS diagnosis for at least 1 year
  • Meet the Budapest criteria for CRPS at the time of the study
Not Eligible

You will not qualify if you...

  • Known allergy to naltrexone or naloxone
  • Use of prescription opioid analgesics or illegal opioid use
  • Current or planned pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Stanford University

Palo Alto, California, United States, 94304

Actively Recruiting

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Research Team

B

Birute Gedrimaite

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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