Actively Recruiting
Low Dose Rosuvastatin Plus Ezetimibe Versus High-dose Rosuvastatin in AMI
Led by Kiyuk Chang, MD,PhD · Updated on 2025-07-30
3548
Participants Needed
7
Research Sites
360 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Combination therapy of rosuvastatin 5mg and ezetimibe 10 mg showed similar achievement rate in decreasing LDL cholesterol level by 50% as single use of rosuvastatin 20 mg. This trial aims to prove non-inferiority of concomitant usage of low dose rosuvastatin and ezetimibe among patients with acute myocardial infarction who went through percutaneous coronary intervention at decreasing major adverse cardiac events compared to the efficacy of single use of high dose rosuvastatin.
CONDITIONS
Official Title
Low Dose Rosuvastatin Plus Ezetimibe Versus High-dose Rosuvastatin in AMI
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 19 years and older
- Diagnosed with myocardial infarction (both ST segment elevation and non-ST segment elevation) treated with percutaneous coronary intervention
- Female patients of childbearing age who agree to mandatory pregnancy testing
- Patients who have agreed to and signed the informed consent form
You will not qualify if you...
- Life expectancy of one year or less due to cancer
- Chronic liver disease
- Sensitivity to rosuvastatin or ezetimibe, or contraindications to these drugs
- Pregnant or breastfeeding
- Female patients unable to use contraception
- Patients on hemodialysis, peritoneal dialysis, or with kidney transplant due to end stage renal disease
- Participation in another clinical trial within 3 months before screening (except non-interventional observational studies)
- Any other reasons deemed inappropriate for the study by the investigators
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 7 locations
1
Bucheon St.Mary Hospital
Bucheon-si, Gyeonggido, South Korea
Actively Recruiting
2
St.Vincent's Hospital
Suwon, Gyeonggido, South Korea
Actively Recruiting
3
Uijeongbu St.Mary's Hospital
Uijeongbu-si, Gyeonggido, South Korea
Actively Recruiting
4
Daejeon St.Mary's Hospital
Daejeon, South Korea
Actively Recruiting
5
Incheon St.Mary's Hospital
Incheon, South Korea
Actively Recruiting
6
Seoul St.Mary's Hospital
Seoul, South Korea, 137-701
Actively Recruiting
7
Yeouido St.Mary Hospital
Seoul, South Korea
Actively Recruiting
Research Team
K
Kiyuk Chang, MD,PhD
CONTACT
E
Eun Ho Choo, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here