Actively Recruiting

Phase 2
Age: 3Months - 21Years
All Genders
NCT06198842

Low Dose Treosulfan Based Conditioning Regimen and PTCy in HSCT for Nijmegen Breakage Syndrome

Led by Federal Research Institute of Pediatric Hematology, Oncology and Immunology · Updated on 2024-01-10

10

Participants Needed

1

Research Sites

271 weeks

Total Duration

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AI-Summary

What this Trial Is About

The aim of the current study is to evaluate the safety and efficacy of low dose treosulfan based conditioning regimen in HSCT with post-transplant cyclophosphamide in Nijmegen breakage syndrome

CONDITIONS

Official Title

Low Dose Treosulfan Based Conditioning Regimen and PTCy in HSCT for Nijmegen Breakage Syndrome

Who Can Participate

Age: 3Months - 21Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 3 months to less than 21 years
  • Diagnosis of Nijmegen Breakage Syndrome
  • Eligible for allogeneic hematopoietic stem cell transplantation
  • Written informed consent signed by a parent or legal guardian
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

HSCT department

Moscow, Russia

Actively Recruiting

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Research Team

D

Dmitry Balashov, MD, PhD

CONTACT

A

Alexandra Laberko, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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