Actively Recruiting

Age: 18Years - 26Years
All Genders
Healthy Volunteers
ID07583940

Cardiovascular Outcomes and Relative Energy Deficiency in Division I HBCU Athletes: CORE-DI Study

Led by North Carolina Agriculture & Technical State University · Updated on 2026-05-13

150

Participants Needed

1

Research Sites

56 weeks

Total Duration

On this page

Sponsors

N

North Carolina Agriculture & Technical State University

Lead Sponsor

N

National Heart, Lung, and Blood Institute (NHLBI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are investigating the link between low energy availability (LEA), where the body lacks enough calories for daily activities and exercise, and cardiometabolic disease (CMD) risks such as high blood pressure and heart disease. This study focuses on Black Division I collegiate athletes, a group that may have a higher risk of serious heart problems despite assumptions of overall good health. The goal is to better understand how LEA affects cardiovascular health and to identify early signs that can inform care and prevention strategies. The study observes over 120 Black Division I athletes aged 18 to 25 years from various sports with an equal number of males and females. Participants will be tested twice, about four months apart, once during their competitive season and once off-season. Measurements include pulse wave velocity (PWV), an indicator of arterial stiffness linked to cardiovascular risk, and assessments of energy availability. Questionnaires will also gather information on social determinants of health (SDOH) such as food security, health literacy, nutrition knowledge, and experiences of discrimination. Throughout the study, participants will undergo non-invasive cardiovascular assessments and complete questionnaires to evaluate factors that may influence cardiovascular risk and energy balance. The study aims to measure how LEA relates to vascular aging and whether social factors affect this relationship. Participants' health and nutrition information will be monitored to support the development of practical strategies to lower cardiovascular risks in this athlete population. The total study duration from enrollment to the second assessment will not exceed 26 weeks.

CONDITIONS

Brief Title

Low Energy Availability and Hypertension in Division I HBCU Athletes

Who Can Participate

Age: 18Years - 26Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged between 18 and 25 years
  • Male and female athletes
  • Division I HBCU collegiate athletes
  • At least 3 years of previous competitive sports experience
Not Eligible

You will not qualify if you...

  • Any known disease or health issue that prevents participation in collegiate sports
  • Orthopedic injuries, concussions, or other conditions that prevent safe testing
  • Individuals under 18 years old
  • Having a pacemaker
  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Monitoring

Duration - Up to 26 weeks

Participants are assessed twice, about 4 months apart, during and outside of their competitive season to measure cardiovascular risk and energy availability along with social determinants of health through questionnaires.

2 visits (in-person)

Trial Site Locations

Total: 1 location

1

North Carolina Agricultural & Technical State University

Greensboro, North Carolina, United States, 27411

Actively Recruiting

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Research Team

T

Troy M Purdom, PhD

C

Catherine Bush, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Louise Capling, Janelle A Gifford, Kathryn L Beck...

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Repeatability of the measurement of aortic pulse wave velocity (aPWV) in the clinical assessment of arterial stiffness in community-dwelling older patients using the Vicorder(®) device.

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Cardiometabolic Health and Carotid-Femoral Pulse Wave Velocity in Children: A Systematic Review and Meta-Regression.

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https://pubmed.ncbi.nlm.nih.gov/31810627

Validating Accuracy of an Internet-Based Application against USDA Computerized Nutrition Data System for Research on Essential Nutrients among Social-Ethnic Diets for the E-Health Era.

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