Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04742881

Low Impact Laparoscopic in Colorectal Resection - PAROS2

Led by University Hospital, Bordeaux · Updated on 2025-05-22

148

Participants Needed

3

Research Sites

193 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To improve post-operative recovery, the concept of Low Impact Laparoscopy was developed in colo-rectal surgery with associating low-pressure pneumoperitoneum and microlaparoscopic surgery. A phase III double-blind, prospective, randomized, controlled, multi-centric trial is designed in the aim to assess the impact of low-pressure pneumoperitoneum with microlaparoscopic instruments on post-operative pain at 24 hours without taking opioids. It is compared with low-pressure laparoscopy with classical laparoscopic instruments in patients undergoing colorectal surgeries.

CONDITIONS

Official Title

Low Impact Laparoscopic in Colorectal Resection - PAROS2

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Scheduled colectomy for malignant or benign pathology
  • Right colon: ileocecal resection, right colectomy, right colectomy extended to the middle of the transverse
  • Left colon: sigmoidectomy, left colectomy
  • Rectal resection without stoma for cancer of the upper rectum
  • Patient operable by laparoscopy (classic or robot assisted for the Standard group)
  • Age 218 years old
  • Patient affiliated to a social security system or beneficiary of the same
  • Informing the patient and obtaining free, informed and written consent, signed by the patient and his investigator
Not Eligible

You will not qualify if you...

  • Laparotomy procedure
  • Patients with electronic implant (ex : pacemaker)
  • Total or Subtotal Colectomy
  • Transverse segmental colectomy
  • Left angular colectomy
  • Proctectomy with stoma or Total Coloproctectomy
  • Patient with stoma
  • Probable realization of a stoma during the operation
  • Procedure associated with colorectal surgery (except appendectomy or liver biopsy)
  • Crohn's disease, Hemorrhagic Rectocolitis (UC)
  • Sigmoiditis
  • EVA before surgery > 3
  • BMI 230
  • ASA > 3
  • History of laparotomy
  • Emergency surgery
  • Pelvic Sepsis or Preoperative Fistula
  • Pregnant woman, likely to be, or breastfeeding
  • Persons deprived of their liberty or under measure of judicial protection (curatorship or guardianship) or unable to give their consent
  • Inability to undergo medical monitoring of the trial for geographic, social or psychological reasons

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 3 locations

1

CH de la Côte Basque

Bayonne, France

Actively Recruiting

2

CHU Bordeaux

Bordeaux, France

Actively Recruiting

3

Ch Libourne

Libourne, France

Actively Recruiting

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Research Team

C

Christophe LAURENT

CONTACT

B

Benjamin FERNANDEZ

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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