Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07173530

Low Level Light Therapy & Skin Pigmentation

Led by University of Houston · Updated on 2025-09-15

40

Participants Needed

1

Research Sites

59 weeks

Total Duration

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AI-Summary

What this Trial Is About

The goal of this clinical trial is to determine if there is a difference in eyelid temperature after low-level light therapy (LLLT) in individuals with different amounts of skin pigmentation and dry eye/meibomian gland disease. Participants will have 3 fifteen minute in office LLLT therapy sessions over a period of approximately 7 to 14 days.

CONDITIONS

Official Title

Low Level Light Therapy & Skin Pigmentation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ability to read and understand the study informed consent in English
  • Age 18 years or older at enrollment
  • Individuals with meibomian gland dysfunction based on clinical signs such as meibum quality score 1-3, meibography score 1-3, tear break up time of 10 seconds or less, or Ocular Surface Disease Index score greater than 12 points
Not Eligible

You will not qualify if you...

  • Active anterior segment eye infections or conditions like bacterial conjunctivitis or microbial keratitis
  • History of systemic diseases causing dry eye, such as Sjogren's syndrome
  • Corneal, refractive, or eyelid surgery within the past 6 months
  • History of corneal ectasia disorders like keratoconus or Pellucid marginal degeneration
  • Eye trauma within the past 6 months
  • Use of LipiFlow, iLux, Meiboflow, IPL, or LLLT treatments within the last 12 months
  • Regular use of photosensitizing medications in the last 30 days
  • Pregnant or breastfeeding women
  • Presence of pigmented lesions, tattoos, or skin cancer near the eyes
  • Unwillingness to have eye photographs or videos taken

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The University of Houston College of Optometry

Houston, Texas, United States, 77204

Actively Recruiting

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Research Team

E

Eric Ritchey, OD, PhD

CONTACT

R

Rachel Redfern, OD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

2

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