Power Training Program for Men Aged 50 and Older With Metastatic Prostate Cancer Receiving Androgen Deprivation Therapy

What this Trial Is About

Researchers are investigating whether a low to moderate load power training program can improve fitness and quality of life for men with metastatic prostate cancer receiving androgen deprivation therapy ADT. This trial focuses on men experiencing bone or lymph node metastases, exploring how power training affects physical side effects like muscle strength, endurance, balance, and mental health. The study also seeks to understand participant experiences through interviews, combining quantitative and qualitative methods for a comprehensive view. Participants are randomly assigned to either a supervised power-oriented resistance training group or a control group receiving usual care with physical activity guidance. The exercise program involves two sessions per week over 24 weeks, emphasizing rapid muscle force production at moderate intensity 40-50% 1RM with low to moderate volume and no training to failure. The control group continues routine care with advice on strength training at home. During the study, participants will complete fitness tests and questionnaires assessing quality of life, mental health, functional capacity, and physical activity levels over six months. Those in the exercise group will also take part in semi-structured interviews to explore psychosocial impacts. Researchers will monitor adverse events and evaluate outcomes such as health-related quality of life, muscle strength, balance, gait speed, and mental health. The total study duration includes the 24-week intervention and a follow-up period to assess lasting effects.

Low to Moderate Load Power Training for Men With Metastatic Prostate Cancer.