Actively Recruiting
Low Serum Creatinine as a Predictor of Prolonged Mechanical Ventilation and Weaning Failure
Led by University Hospital Ostrava · Updated on 2026-02-05
492
Participants Needed
2
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The main objective of the study is to determine whether a subnormal serum creatinine value upon admission to the Post-ICU Care Unit predicts the need for prolonged ventilatory support. A parallel objective of the study is to determine whether exogenous in-take of the dietary supplement creatine in patients with subnormal serum creatinine value is associated with a shortened duration of ventilatory support and improved patients outcome.
CONDITIONS
Official Title
Low Serum Creatinine as a Predictor of Prolonged Mechanical Ventilation and Weaning Failure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients 18 years of age or older
- Patients admitted to post-ICU care units at Chronicare Group a.s. in the Czech Republic within 12 months
You will not qualify if you...
- Patients who are unlikely to be weaned from ventilatory support
- Patients in palliative care or with a survival probability of less than 3 months
- Patients with advanced malignancy
- Patients with a history of chronic kidney disease
- Patients with a history of chronic liver disease
- Patients with supranormal serum creatinine on admission to the post-ICU care unit
- Patients who refused to sign the Informed Consent with participation in the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Chronicare Mund s.r.o.
Brno, Czechia, 621 00
Actively Recruiting
2
Chronicare s.r.o.
Milovice, Czechia, 289 24
Actively Recruiting
Research Team
J
Jiří Hynčica
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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