Actively Recruiting
LSM and SSM for the Diagnosis of CSPH: a Prospective Cohort Study
Led by McGill University Health Centre/Research Institute of the McGill University Health Centre · Updated on 2026-03-12
200
Participants Needed
1
Research Sites
255 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational study is to assess non-invasive tools' efficacy in predicting portal hypertension-related complications in individuals with advanced chronic liver disease. The main question it aims to answer are: \- what are the cut-off values for non-invasive tests (NITs) (including LSM, SSM) that predict the presence and occurrence of hepatic decompensation in individuals with advanced chronic liver disease? Participants will undergo regular study visits involving non-invasive tests (LSM, SSM) and assessments to monitor hepatic decompensation over the study period.
CONDITIONS
Official Title
LSM and SSM for the Diagnosis of CSPH: a Prospective Cohort Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age above 18 years old
- Advanced chronic liver disease defined as Liver Stiffness Measurement (LSM) of 10 kPa or higher
- Ability to provide informed consent
You will not qualify if you...
- Previous transjugular intrahepatic portosystemic shunt (TIPS) procedure
- History of liver transplantation
- Abnormalities of the porto-mesenteric system such as portal vein thrombosis, splenic vein thrombosis, splenectomy, portal cavernomatous transformation, or porto-caval shunts
- Presence of hematological malignancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
McGill University Health Centre
Montreal, Quebec, Canada, H3G1A4
Actively Recruiting
Research Team
A
Amine Benmassaoud, MD
CONTACT
O
Olivia Geraci, BSc
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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