Actively Recruiting
LT for Unresectable Colorectal Liver Metastasis
Led by Seoul National University Hospital · Updated on 2022-09-06
20
Participants Needed
1
Research Sites
192 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Unlike hepatocellular carcinoma, liver transplantation in patients with liver metastasis from colorectal cancer is limited in only few centers. Previously, it was not generally implemented due to lack of organs and high recurrence rates after transplantation. However, due to progressive development in treatments, good results such as increased survival rates can be expected even in liver transplant patients with liver metastasis from colorectal cancer, which is known to have poor prognosis. Therefore, the purpose of this study is to analyze the efficacy of liver transplantation as an alternative treatment for liver metastasis from colorectal cancer.
CONDITIONS
Official Title
LT for Unresectable Colorectal Liver Metastasis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Proven colorectal cancer liver metastases without any other treatment such as immunotherapy, chemotherapy, surgical resection, or radiofrequency ablation
- Metastasis isolated to the liver only
- Selected as a liver transplant recipient by a multidisciplinary team
- Have a willing, healthy living donor for liver transplantation
- Willing and able to provide written informed consent
You will not qualify if you...
- Pregnant women
- Known history of human immunodeficiency virus (HIV) infection
- Active peptic ulcer within 2 weeks before transplantation
- Persistent colorectal cancer after colon resection
- Hemodynamically unstable before liver transplantation
- Progression of liver metastasis at any time before transplant surgery as assessed by a multidisciplinary meeting
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Seoul National University Hospital
Seoul, South Korea, 03080
Actively Recruiting
Research Team
Y
YoungRok Choi, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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