Actively Recruiting
Lumbar Drain vs Extraventricular Drain to Prevent Vasospasm in Subarachnoid Hemorrhage
Led by University of California, San Diego · Updated on 2025-03-04
100
Participants Needed
1
Research Sites
522 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Vasospasm is a common complication after rupture of intracranial aneurysms causing devastating neurologic deficits and death. Vasospasm has been directly associated with the amount of subarachnoid blood inside the basal cisterns. Prior literature has attempted to refine treatment of ruptured intracranial aneurysms but does not have clear guidelines on the optimal method to drain subarachnoid blood. Two methods, extraventricular drain (EVD) and lumbar drain (LD) have been compared retrospectively yet remain controversial as to which method is optimal in reducing subarachnoid blood and preventing vasospasm. This study would be a prospective randomized trial in which patients would be assigned to EVD or LD and observed to see if one method of intervention is associated with preventing clinical vasospasm, decreasing subarachnoid blood, shortening overall ICU stay, and reducing the need for a permanent ventriculoperitoneal shunt. The conclusions of this study may identify an optimal treatment modality to benefit all future patients with ruptured intracranial aneurysms.
CONDITIONS
Official Title
Lumbar Drain vs Extraventricular Drain to Prevent Vasospasm in Subarachnoid Hemorrhage
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients admitted at UCSD Medical Center with grade II, III, or IV subarachnoid hemorrhage
- Patients with aneurysmal subarachnoid hemorrhage confirmed by radiographic evidence
You will not qualify if you...
- Patients under 18 years of age
AI-Screening
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Trial Site Locations
Total: 1 location
1
UCSD Medical Center
San Diego, California, United States, 92103
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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