Actively Recruiting

Phase Not Applicable
FEMALE
NCT07447414

Luminal Breast Cancer Cryoablation

Led by Lucía Graña López · Updated on 2026-04-16

140

Participants Needed

1

Research Sites

138 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

LUBRECA will evaluate the safety and efficacy of cryoablation with liquid nitrogen to treat cT1cN0 luminal breast cancer diagnosed in postmenopausal women

CONDITIONS

Official Title

Luminal Breast Cancer Cryoablation

Who Can Participate

FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Postmenopausal women diagnosed with invasive breast cancer by core needle biopsy or vacuum-assisted biopsy
  • Unifocal tumor
  • Lesion size 64 2 cm on ultrasound and contrast enhanced mammography
  • No axillary lymphadenopathy on ultrasound
  • No axillary lymph node involvement on ultrasound
  • Luminal tumor (estrogen and/or progesterone receptor positive)
  • HER2 negative
  • Signed informed consent
Not Eligible

You will not qualify if you...

  • Infiltrating lobular carcinoma
  • Extensive in situ component
  • Multifocality or multicentricity
  • Contraindication for contrast mammography
  • Not candidate for surgery
  • Distant metastasis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hospital Universitario Lucus Augusti

Lugo, Lugo, Spain, 27003

Actively Recruiting

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Research Team

L

Lucía Graña López, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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