Actively Recruiting

Phase Not Applicable
Age: 65Years +
All Genders
ID06807983

Impact of a Management Strategy for Acute Dyspnea in Elderly Subjects Using Lung and Cardiac Ultrasonography

Led by University Hospital, Toulouse · Updated on 2025-12-04

504

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating a management strategy for acute dyspnea in elderly patients using lung and cardiac ultrasonography. Acute dyspnea, a common and serious reason for emergency admission with high mortality, is often hard to diagnose quickly because its causes vary widely. This study aims to see if using ultrasonography at the bedside by emergency physicians can reduce delays in diagnosis and treatment for elderly patients with acute breathing difficulties. Participants will be randomly assigned to one of two groups: a clinical ultrasound group where lung and cardiac ultrasonography guides diagnosis and treatment immediately at the bedside, or a standard care group receiving usual diagnostic and therapeutic procedures. Emergency physicians trained in this ultrasound technique will perform the examinations, and treatments initiated in the emergency department will be recorded for comparison with final diagnoses. During the study, participants will be assessed for therapeutic adequacy within the first hour and diagnostic accuracy up to four hours after emergency department discharge. Researchers will also track emergency department stay length, hospital stay after emergency care, days alive outside the hospital within 30 days, and care costs. Consent will be obtained, and monitoring will continue through day 30 to evaluate the outcomes and safety of the management strategies.

CONDITIONS

Brief Title

LUng and Cardiac Ultrasound for REspiratory Distress in ElDerly

Who Can Participate

Age: 65Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged over 65 years
  • Affiliated with the French social security system
  • Presenting to the emergency department with acute dyspnea starting less than 14 days ago
  • Showing severity signs before or at triage, including respiratory rate of 22 or more and oxygen saturation below 92% on room air
  • Emergency physician enrolling the patient must be the treating physician and trained in lung and cardiac ultrasonography
  • Written informed consent provided by the patient or their legal representative
Not Eligible

You will not qualify if you...

  • Dyspnea caused by chest trauma
  • Dyspnea clearly related to COVID-19 infection
  • Known pulmonary fibrosis or lung cancer
  • Prior administration of specific treatment for dyspnea before inclusion
  • Immediate need for endotracheal intubation
  • Patients identified as being at end-of-life
  • Individuals under legal guardianship or deprived of liberty

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Up to 4 hours

Participants undergo diagnostic assessment using lung and cardiac ultrasonography or standard care to evaluate the cause of acute dyspnea.

1 visit (in-person) during emergency department stay

Long-term Monitoring

Duration - 30 days

Participants are followed for outcomes including hospital stay duration, days alive outside hospital, and care costs up to 30 days after emergency department discharge.

Follow-up assessments up to Day 30

Trial Site Locations

Total: 1 location

1

UHToulouse

Toulouse, France

Actively Recruiting

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Research Team

M

Manon Hebrard

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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Published Research Related To This Trial

Lung and cardiac ultrasound for respiratory distress in the elderly: study protocol of the LUC REED stepped-wedge cluster randomised trial.

Frederic Balen, Manon Hebrard, Clément Delmas...

https://pubmed.ncbi.nlm.nih.gov/40819865