Actively Recruiting
Study Comparing Lung Recruitment Effects of Chest Physiotherapy Using Two Ventilation Modes in Mechanically Ventilated Patients
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2026-01-15
40
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are evaluating the effects of respiratory physiotherapy in patients who are under invasive mechanical ventilation in intensive care. This study compares the lung recruitment and other respiratory effects during chest physiotherapy sessions performed under two different ventilatory modes Volume Assist Control Ventilation V-ACV and pressure support ventilation PSV. The goal is to understand how ventilatory settings influence physiotherapy outcomes, especially in patients with abundant mucus requiring airway clearance. Participants receive a standardized respiratory physiotherapy intervention consisting of rib cage compressions applied to the chest while positioned supine with the head of the bed elevated to 35 degrees. Each patient undergoes two sessions in one day one in the morning and one in the afternoon with one session performed under V-ACV and the other under PSV, in randomized order. The sessions involve 7 series of 3 brief, vigorous compressions during expiration, spaced by about 10 respiratory cycles. During the study, researchers measure lung volume changes, oxygen levels, respiratory mechanics, mucus volume and weight, regional lung ventilation, heart rate, blood pressure, and other breathing parameters before, during, and after each physiotherapy session. Measurements are taken at specific times including 5 minutes before, during, immediately after, and up to 1 hour following sessions. This detailed monitoring helps assess the effectiveness and patient tolerance of the physiotherapy under different ventilatory modes.
CONDITIONS
Brief Title
Lung Recruitment During Chest Physiotherapy in Mechanically Ventilated Patients
Research Team
G
Guillaume Pr CARTEAUX, MD,PhD
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