Actively Recruiting

Phase Not Applicable
FEMALE
NCT07261956

Lung Ultrasound for the Detection of Volume Overload in Patients With Severe Preeclampsia

Led by Saint Thomas Hospital, Panama · Updated on 2025-12-03

202

Participants Needed

1

Research Sites

22 weeks

Total Duration

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AI-Summary

What this Trial Is About

This research aims to evaluate the usefulness of lung ultrasound (LUS) for detecting and monitoring fluid overload in patients with severe preeclampsia. Severe preeclampsia is a leading cause of maternal death and illness worldwide, often causing fluid buildup that can lead to a serious complication called pulmonary edema, especially after delivery. The study will be a prospective, longitudinal observational study with a diagnostic validation component. It will involve patients with a diagnosis of severe preeclampsia who meet specific inclusion criteria. Each participant will undergo a clinical exam and a lung ultrasound, which will assess eight zones of the lungs. The total number of B-lines-a sign of interstitial edema-will be documented. Data will be collected at three key times: upon admission, in the immediate postpartum period (within 24 hours of delivery), and 7-10 days postpartum. The results from the LUS will be compared to clinical signs like shortness of breath, rapid breathing, crackling sounds in the lungs, and oxygen saturation levels. The expected impact of this research is to provide evidence that LUS is a valuable, non-invasive, and accessible tool for the early detection of pulmonary congestion in patients with severe preeclampsia. This could lead to improved clinical decision-making and a reduction in maternal respiratory complications.

CONDITIONS

Official Title

Lung Ultrasound for the Detection of Volume Overload in Patients With Severe Preeclampsia

Who Can Participate

FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Preeclampsia with severe features
  • Gestational age between 24 weeks and 41 weeks
Not Eligible

You will not qualify if you...

  • Chronic lung disease
  • Known heart disease
  • Diagnosis of lung edema at admission
  • Body mass index greater than 40
  • Need for immediate delivery

AI-Screening

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Trial Site Locations

Total: 1 location

1

Saint Thomas Hospital

Panama City, Provincia de Panamá, Panama

Actively Recruiting

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Research Team

A

Anna C Figueroa, MD

CONTACT

A

Adriana Martinz, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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